欧洲对痴呆症患者的非正式护理。
Informal care for people with dementia in Europe.
作者信息
Handels Ron, Hataiyusuk Somboon, Wimo Anders, Sköldunger Anders, Bakker Christian, Bieber Anja, Ciccone Alfonso, Defanti Carlo Alberto, Fabbo Andrea, Fascendini Sara, Frölich Lutz, Gervès-Pinquié Chloé, Gonçalves-Pereira Manuel, Irving Kate, Koopmans Raymond, Mecocci Patrizia, Merlo Paola, Michalowsky Bernhard, Peters Oliver, Pijnenburg Yolande, Ribeiro Óscar, Salbaek Geir, Schwarzkopf Larissa, Verbeek Hilde, de Vugt Marjolein, Woods Bob, Zanetti Orazio, Winblad Bengt, Jönsson Linus
机构信息
Alzheimer Centre Limburg, Faculty of Health Medicine and Life Sciences, Mental Health and Neuroscience Research Institute, Department of Psychiatry and Neuropsychology, Maastricht University, Universiteitssingel 40, 6200 MD, Maastricht, The Netherlands; Division of Neurogeriatrics, Department of Neurobiology Care Sciences and Society; Karolinska Institutet; Sweden; BioClinicum J9:20, Akademiska stråket, 171 64 Solna, Sweden.
Alzheimer Centre Limburg, Faculty of Health Medicine and Life Sciences, Mental Health and Neuroscience Research Institute, Department of Psychiatry and Neuropsychology, Maastricht University, Universiteitssingel 40, 6200 MD, Maastricht, The Netherlands; Department of Psychiatry, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, 10700 Bangkok, Thailand.
出版信息
J Prev Alzheimers Dis. 2025 Jan;12(1):100015. doi: 10.1016/j.tjpad.2024.100015. Epub 2025 Jan 1.
INTRODUCTION
Informal care estimates for use in health-economic models are lacking. We aimed to estimate the association between informal care time and dementia symptoms across Europe.
METHODS
A secondary analysis was performed on 13,529 observations in 5,369 persons from 9 European pooled cohort or trial studies in community-dwelling persons with dementia. A mixed regression model was fitted to time spent on instrumental or basic activities of daily living using disease severity and demographic characteristics.
RESULTS
Daily informal care time was 0.5 hours higher in moderate compared to mild and 1.3h higher in severe compared to mild cognitive impairment. Likewise, this was 1.2h and 2.7h for functional disability and 0.3h and 0.6h for behavioral symptoms in the same directions.
DISCUSSION
Estimates can be used in both single- and multi-domain health-economic models for dementia in European settings.
引言
用于健康经济模型的非正式护理估计数据匮乏。我们旨在估计欧洲各地非正式护理时间与痴呆症状之间的关联。
方法
对来自9项欧洲痴呆症社区居民汇总队列研究或试验研究的5369人进行了13529次观察的二次分析。使用疾病严重程度和人口统计学特征，对花费在日常生活工具性或基本活动上的时间进行混合回归模型拟合。
结果
与轻度认知障碍相比，中度认知障碍患者的每日非正式护理时间高出0.5小时，重度认知障碍患者高出1.3小时。同样，在功能残疾方面，分别高出1.2小时和2.7小时，行为症状方面分别高出0.3小时和0.6小时。
讨论
这些估计值可用于欧洲环境中痴呆症的单领域和多领域健康经济模型。
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