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三叉神经痛:恢复生活质量的治疗策略。

Trigeminal neuralgia: therapeutic strategies to restore quality of life.

作者信息

Villegas Díaz Diego, Guerrero Alvarado Gabriela, López Medina Alan, Gómez Clavel José Francisco, García Muñoz Alejandro

机构信息

Aragon Dental Clinic, Faculty of Higher Studies Iztacala, National Autonomous University of Mexico, 057130 Nezahualcóyotl, EM, Mexico.

Research Laboratory in Dental Education, Dental Surgeon Career, FES Iztacala, UNAM, 54090 Tlalnepantla, EM, Mexico.

出版信息

J Oral Facial Pain Headache. 2024 Sep;38(3):32-37. doi: 10.22514/jofph.2024.024. Epub 2024 Sep 12.

DOI:10.22514/jofph.2024.024
PMID:39800569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11810647/
Abstract

Trigeminal neuralgia (TN) usually affects the maxillary and mandibular branches of the fifth cranial nerve. Although the condition is primarily unilateral, few cases of bilateral manifestation have been reported. TN is uncommon; however, it significantly affects patients' quality of life because the neuropathic pain worsens over time. Paroxysmal pain is triggered by mechanical stimuli or environmental factors. Diagnosis is usually based on clinical findings, including pain triggered by palpation of distinct areas; nevertheless, imaging studies, such as magnetic resonance imaging, are always used to rule out a secondary cause. TN can be caused by several factors, such as trauma and neurovascular compression, or could be idiopathic, which complicates its treatment. Although several studies focused on TN have been reported, a treatment modality with 100% efficacy is lacking. The first-line treatment is pharmacological; however, surgery may be required if symptoms persist.

摘要

三叉神经痛(TN)通常影响第五对脑神经的上颌支和下颌支。虽然该病主要为单侧发病,但双侧表现的病例也有少量报道。TN并不常见;然而,它会显著影响患者的生活质量,因为神经病理性疼痛会随着时间的推移而加重。阵发性疼痛由机械刺激或环境因素触发。诊断通常基于临床表现,包括触诊特定区域引发的疼痛;不过,影像学检查,如磁共振成像,总是用于排除继发性病因。TN可由多种因素引起,如外伤和神经血管压迫,也可能是特发性的,这使其治疗变得复杂。虽然已经报道了几项关于TN的研究,但仍缺乏100%有效的治疗方式。一线治疗是药物治疗;然而,如果症状持续,则可能需要手术治疗。

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A Systematic Review of the Role of Magnetic Resonance Imaging in the Diagnosis and Detection of Neurovascular Conflict in Patients With Trigeminal Neuralgia.磁共振成像在三叉神经痛患者神经血管冲突诊断与检测中作用的系统评价
Cureus. 2023 Sep 3;15(9):e44614. doi: 10.7759/cureus.44614. eCollection 2023 Sep.
2
Acupuncture for the treatment of trigeminal neuralgia: A systematic review and meta-analysis.针刺治疗三叉神经痛的系统评价和荟萃分析。
Complement Ther Clin Pract. 2023 Aug;52:101763. doi: 10.1016/j.ctcp.2023.101763. Epub 2023 May 2.
3
Diagnosis and treatment of trigeminal neuralgia: Consensus statement from the Spanish Society of Neurology's Headache Study Group.三叉神经痛的诊断与治疗:西班牙神经学会头痛研究组的共识声明
Neurologia (Engl Ed). 2023 Jun;38 Suppl 1:S37-S52. doi: 10.1016/j.nrleng.2023.04.005. Epub 2023 Apr 26.
4
Current Applications of Ablative Therapies for Trigeminal Neuralgia.目前的消融疗法在三叉神经痛中的应用。
Neurosurg Clin N Am. 2023 Apr;34(2):285-290. doi: 10.1016/j.nec.2022.12.005.
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Microvascular Decompression Versus Gamma Knife Surgery in Patients with Drug-Resistant Trigeminal Neuralgia: A Systematic Review and Meta-Analysis.微血管减压术与伽玛刀手术治疗药物难治性三叉神经痛的疗效比较:系统评价与荟萃分析。
World Neurosurg. 2022 Nov;167:67-73. doi: 10.1016/j.wneu.2022.08.020. Epub 2022 Aug 13.
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