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盆底康复对结直肠癌治疗后低位前切除综合征的影响。

The Effect of Pelvic Floor Rehabilitation on Low Anterior Resection Syndrome After Colorectal Cancer Treatment.

作者信息

Jones Shelby, Edie Alison, Troop Emily, Hill Joshua S, Thompson Julie A

机构信息

From Atrium Health Levine Cancer Institute, Charlotte, North Carolina.

Duke University School of Nursing, Durham, North Carolina.

出版信息

J Adv Pract Oncol. 2024 May 22:1-12. doi: 10.6004/jadpro.2024.15.8.4.

Abstract

PURPOSE

Low anterior resection (LAR) is the preferred surgical treatment of rectosigmoid or rectal cancers. However, it is often associated with bowel dysfunction, which is termed low anterior resection syndrome (LARS). Daily bowel dysfunction symptoms have a detrimental effect on quality of life (QOL). Pelvic floor rehabilitation (PFR) can improve pelvic floor function and QOL among patients with LARS. This quality improvement (QI) project seeks to assess the prevalence of LARS and develop and incorporate PFR for the treatment and prevention of LARS.

METHODS

A convenience sample of 20 patients met project inclusion. Thirteen patients participated. Individuals were categorized by diagnostic risk: low risk, high risk, and established. The intervention included 1-hour PFR sessions with the physical therapist (PT) and 5 minutes of daily self-led pelvic floor muscle exercises. Outcomes questionnaires included the LARS Score and Fecal Incontinence Quality of Life (FIQOL) Scale. Data were collected both pre- and post-colorectal cancer treatment.

RESULTS

The overall prevalence of LARS was 76.9%, which was significantly higher than the retrospective cohort comparison rate of 21.8% ( < .001). The prevalence of major LARS was 89%, 83%, and 50% at the initial, second, and third sessions, respectively, representing a 44% relative decrease. Embarrassment was significantly affected among individuals with major LARS, although ongoing PFR facilitated improvement.

CONCLUSION

PFR is a valuable adjunct therapy for LARS, with continued sessions decreasing the overall prevalence among the cohort. Major LARS negatively impacts QOL measures early on in treatment but improves with continued PFR.

摘要

目的

低位前切除术(LAR)是乙状结肠或直肠癌的首选手术治疗方法。然而,它常与肠道功能障碍相关,即所谓的低位前切除综合征(LARS)。日常肠道功能障碍症状会对生活质量(QOL)产生不利影响。盆底康复(PFR)可改善LARS患者的盆底功能和生活质量。本质量改进(QI)项目旨在评估LARS的患病率,并开发并纳入PFR用于LARS的治疗和预防。

方法

20例患者的便利样本符合项目纳入标准。13例患者参与。个体按诊断风险分类:低风险、高风险和确诊。干预措施包括与物理治疗师(PT)进行1小时的PFR治疗,以及每天5分钟的自主盆底肌肉锻炼。结果问卷包括LARS评分和大便失禁生活质量(FIQOL)量表。在结直肠癌治疗前后均收集数据。

结果

LARS的总体患病率为76.9%,显著高于回顾性队列比较率21.8%(P<0.001)。主要LARS的患病率在初次治疗时为89%,第二次治疗时为83%,第三次治疗时为50%,相对下降了44%。主要LARS患者的尴尬感受到显著影响,尽管持续的PFR有助于改善。

结论

PFR是LARS的一种有价值的辅助治疗方法,持续治疗可降低队列中的总体患病率。主要LARS在治疗早期对生活质量指标有负面影响,但随着PFR的持续进行会有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3682/11715399/c5a3f83aaa1c/jadpro-2024-15-8-4-g001.jpg

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