Zheng Ruoxuan, Zeng Xiangman, Shen Ruiting, Wang Yueqiu, Liu Jing, Zhang Mingchen
Department of Endocrinology and Metabolism, Ningbo No.2 hospital, Ningbo, Zhejiang Province, People's Republic of China.
School of Medicine, Ningbo University, Ningbo, Zhejiang Province, People's Republic of China.
Diabetes Metab Syndr Obes. 2025 Jan 7;18:61-73. doi: 10.2147/DMSO.S501132. eCollection 2025.
To identify the key populations for Hospital Hyperglycemia (HH) management and to assess recent trends in the management of HH.
This retrospective study analyzed 1,136,092 point-of-care blood glucose (POC-BG) measurements from 40,758 patients with HH in non-intensive care unit (non-ICU) wards at Ningbo No.2 hospital from January 2020 to December 2022. We compared glucose monitoring and management across varying years, age groups, and hospital departments.
The overall incidence of HH was 16.87%. From 2020 to 2022, the number of patients with HH increased from 9,893 to 15,639, accompanied by a marginal improvement in average BG levels (slope difference, -8.137E-09 [CI, -8.742E-09 to -7.531E-09]; p <0.001). In the ≥80 years group, the median BG was 9.4 mmol/L, significantly higher than in other age groups (p<0.001). Hypoglycemia in this group was most frequently detected during nighttime and bedtime, with an incidence of 2.67%, significantly higher than at other times of the day (p<0.001). The daily POC-BG testing rate was significantly higher in the medical ward group than it in the surgical ward group (57.9% vs 51.7%, p<0.05). Proportions of glycemic targets days were 35.66% and 39.90% in the medical wards on day 1 and day 7, respectively (Day 7 39.90% vs Day 1 35.66%, p>0.05), and 46.16% and 45.07% in the surgical wards (Day 7 45.07% vs Day 1 46.16%, p>0.05), showing no significant improvements in glycemic control. Endocrinology consultations occurred at rates of 14.2% in the medical wards and 14.9% in the surgical wards (p>0.05).
Although the prevalence of HH is consistently high and the number of affected patients continues to rise, modest improvements in glycemic management have been observed. However, control among the elderly remains poor, with a notably high risk of hypoglycemia during nighttime and bedtime periods.
确定医院高血糖（HH）管理的关键人群，并评估HH管理的近期趋势。
这项回顾性研究分析了2020年1月至2022年12月期间宁波第二医院非重症监护病房（非ICU）中40758例HH患者的1136092次即时血糖（POC-BG）测量值。我们比较了不同年份、年龄组和医院科室的血糖监测与管理情况。
HH的总体发生率为16.87%。从2020年到2022年，HH患者数量从9893例增加到15639例，同时平均血糖水平有轻微改善（斜率差异，-8.137E-09 [CI，-8.742E-09至-7.531E-09]；p<0.001）。在≥80岁年龄组中，血糖中位数为9.4 mmol/L，显著高于其他年龄组（p<0.001）。该组低血糖最常发生在夜间和就寝时间，发生率为2.67%，显著高于一天中的其他时间（p<0.001）。内科病房组的每日POC-BG检测率显著高于外科病房组（57.9%对51.7%，p<0.05）。内科病房第1天和第7天血糖达标天数的比例分别为35.66%和39.90%（第7天39.90%对第1天35.66%，p>0.05），外科病房分别为46.16%和45.07%（第7天45.07%对第1天46.16%，p>0.05），血糖控制无显著改善。内分泌科会诊在内科病房的发生率为14.2%，在外科病房为14.9%（p>0.05）。
尽管HH的患病率一直很高且受影响患者数量持续增加，但已观察到血糖管理有适度改善。然而，老年人的血糖控制仍然较差，夜间和就寝时间低血糖风险尤其高。
