Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia.
Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Perth, Western Australia, Australia.
Int J Med Sci. 2021 Oct 3;18(16):3744-3747. doi: 10.7150/ijms.63381. eCollection 2021.
This study aimed to assess the incidence and associates of hypoglycemia in patients transferred after stabilization on an Acute Medical Unit to two general medical or two geriatric wards at an urban Australian hospital. In a six-month audit representing 20,284 patient-days of observation, 59 inpatients experienced hypoglycaemia (blood glucose ≤3.9 mmol/L) during 65 hospitalizations. Inpatients experiencing hypoglycemia accounted for 7.2% of all inpatient bed-days, a figure that was greater for general medical (9.2% of bed-days) compared with geriatric (6.0% of bed-days) wards (<0.001). Inpatient hypoglycemia often had no precipitant such as a missed/delayed meal, occurred disproportionately at night (41% of episodes), was severe (blood glucose ≤3.0 mmol/L) in one-third of cases, and appeared more frequent in patients with psychiatric/cognitive issues. These data highlight the ongoing issue of hypoglycemia in relatively stable inpatients in an era of blood glucose-lowering therapies associated with a low rate of this acute metabolic complication.
本研究旨在评估在澳大利亚一家城市医院的急性内科病房稳定后转至两个普通内科病房或两个老年病房的患者发生低血糖的发生率和相关因素。在为期六个月的审计中，观察了 20284 名患者住院 65 天，59 名住院患者发生低血糖（血糖≤3.9mmol/L）。发生低血糖的住院患者占所有住院患者住院天数的 7.2%，普通内科（占住院患者住院天数的 9.2%）比老年科（占住院患者住院天数的 6.0%）更高（<0.001）。住院患者低血糖往往没有明显的诱因，如漏餐/延迟用餐，夜间发作比例过高（41%），三分之一的病例血糖严重降低（≤3.0mmol/L），而且在有精神/认知问题的患者中更为常见。这些数据突出了在使用降低血糖的治疗方法的时代，相对稳定的住院患者中持续存在低血糖的问题，而且这种急性代谢并发症的发生率较低。
