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隐匿性节律:妊娠剧吐诱发心律失常的复杂病例

Hidden Rhythms: A Complex Case of Hyperemesis Gravidarum-Induced Arrhythmias.

作者信息

Anderson Todd R, Carletto Emily J, Barreto-Nadal Valeria, Joubert Eloise, Schutzer David

机构信息

Obstetrics and Gynecology, Campbell University School of Osteopathic Medicine, Lillington, USA.

Pediatrics, Campbell University School of Osteopathic Medicine, Lillington, USA.

出版信息

Cureus. 2024 Dec 11;16(12):e75548. doi: 10.7759/cureus.75548. eCollection 2024 Dec.

Abstract

Hyperemesis gravidarum (HG) is a severe condition marked by intense nausea and vomiting during pregnancy, which is different from typical morning sickness. It is marked by weight loss exceeding 5% of pre-pregnancy weight, ketonuria, dehydration, electrolyte imbalances, and in some cases, arrhythmias - primarily linked to electrolyte disturbances. Treatment typically involves conservative measures such as small, bland meals, medications like metoclopramide and ondansetron, and correction of electrolyte abnormalities. This case study presents a 29-year-old female, G5P2022, who arrived at the ED with severe nausea, vomiting, intermittent chest pain, and palpitations lasting five days. She was confirmed to be seven weeks and five days pregnant. Her medical history included preeclampsia with severe features and HG in prior pregnancies. Initial evaluations, including CBC, complete metabolic panel, and troponin levels, were unremarkable, with normal electrolytes. However, an ECG revealed multiple arrhythmias. Cardiology and electrophysiology consultations recommended outpatient follow-up. This case highlights the serious risks HG poses to both maternal and fetal health. Although arrhythmias are a recognized complication of HG, this case is notable for their occurrence despite normal electrolyte levels, emphasizing the complex interplay between HG and cardiac function.

摘要

妊娠剧吐(HG)是一种严重的病症,其特征为孕期出现强烈的恶心和呕吐,这与典型的孕吐不同。其标志为体重减轻超过孕前体重的5%、酮尿症、脱水、电解质失衡,在某些情况下还会出现心律失常——主要与电解质紊乱有关。治疗通常包括保守措施,如少食清淡食物、使用甲氧氯普胺和昂丹司琼等药物,以及纠正电解质异常。本病例研究介绍了一名29岁的女性,孕5产2022,因严重恶心、呕吐、间歇性胸痛和心悸持续五天而抵达急诊室。她被确诊怀孕7周零5天。她的病史包括既往妊娠时患有重度子痫前期和妊娠剧吐。初步检查,包括全血细胞计数、全套代谢检查和肌钙蛋白水平,均无异常,电解质正常。然而,心电图显示有多种心律失常。心脏病学和电生理会诊建议门诊随访。本病例突出了妊娠剧吐对母婴健康构成的严重风险。虽然心律失常是妊娠剧吐公认的并发症,但本病例的显著之处在于尽管电解质水平正常仍出现了心律失常,强调了妊娠剧吐与心脏功能之间复杂的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ef8/11723710/3eb956a804bf/cureus-0016-00000075548-i01.jpg

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