Olaniyi Seyi A, Ali Muhammad, Sharma Abhimanyu, Kazmi Syeda Areeba Hussain, Raj Rohan, Kaur Parvinder, Islam Hamza, Alameddine Selim, Singh Mansi
Medicine and Surgery, Obafemi Awolowo University, Ile Ife, NGA.
Internal Medicine, Riphah University, Rawalpindi, PAK.
Cureus. 2024 Dec 11;16(12):e75543. doi: 10.7759/cureus.75543. eCollection 2024 Dec.
The purpose of this study is to evaluate the impact of foveal bulge presence on visual acuity (VA) in patients with diabetic macular edema (DME) and retinal vein occlusion (RVO).
Spectral-domain optical coherence tomography (SD-OCT) scans were conducted on 22 DME patients and 20 RVO patients. Ordinary least squares (OLS) regression was employed to analyze the association between VA and the presence of the foveal bulge, as well as factors such as sex, age, central foveal thickness, various line scans of the fovea, and the external limiting membrane (ELM).
In DME patients, the β value associated with foveal bulge presence was 10.2, while the β value for ELM presence was 36.19. For RVO patients, the β value for foveal bulge presence was 18.71. In the combined analysis of DME and RVO patients, VA increased by 14.24 letters with the presence of a foveal bulge.
The presence of a foveal bulge significantly enhances VA in patients with resolved DME and RVO. Our findings indicate that the increase in VA is more pronounced in RVO patients compared to those with DME. Additionally, the presence of the foveal bulge, ELM, and sex can serve as predictors for VA outcomes in these patient populations.
本研究旨在评估黄斑隆起的存在对糖尿病性黄斑水肿(DME)和视网膜静脉阻塞(RVO)患者视力(VA)的影响。
对22例DME患者和20例RVO患者进行了光谱域光学相干断层扫描(SD - OCT)。采用普通最小二乘法(OLS)回归分析视力与黄斑隆起的存在之间的关联,以及性别、年龄、中心凹厚度、黄斑的各种线扫描和外界膜(ELM)等因素。
在DME患者中,与黄斑隆起存在相关的β值为10.2,而与ELM存在相关的β值为36.19。对于RVO患者,与黄斑隆起存在相关的β值为18.71。在DME和RVO患者的联合分析中,黄斑隆起存在时视力提高了14.24个字母。
黄斑隆起的存在显著提高了已缓解的DME和RVO患者的视力。我们的研究结果表明,与DME患者相比,RVO患者的视力提高更为明显。此外,黄斑隆起、ELM的存在以及性别可作为这些患者群体视力结果的预测指标。