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中国广西首例小儿骨髓移植患儿的检测与感染控制情况

The First Case of Detection and Infection Control in a Pediatric Bone Marrow Transplant Child Patient in Guangxi, China.

作者信息

Yang Liu, Hong Kaiting, Luo Jiajia, Wang Lili, Zhang Lei, Jiang Lijun, Peng Qiliu, Guo Jian

机构信息

Department of Clinical Laboratory, Guangxi International Zhuang Medicine Hospital, Nanning, Guangxi, People's Republic of China.

Department of Laboratory Medicine, Zhoushan Women and Children Hospital, Zhoushan, People's Republic of China.

出版信息

Infect Drug Resist. 2025 Jan 6;18:127-133. doi: 10.2147/IDR.S490696. eCollection 2025.

Abstract

is an emerging yeast species and an opportunistic pathogen. Due to its multi-drug resistance and ability to colonize and transmit, it poses a significant risk for outbreaks in medical institutions. In this study, we report the first case of detected in a pediatric bone marrow transplant child patient in Guangxi, China. was isolated from urine and identified using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, and the isolate belonged to clade I using sequencing. We have implemented stringent infection control measures including personal protective equipment and treatment in a single room, and conducted regular surveillance screening of patients' body surfaces, as well as those of related medical and logistics personnel, medical equipment, and surrounding environmental surfaces. These measures aim to effectively control the colonization of in patients, prevent its spread within hospitals, and ensure the quality of diagnosis and treatment for patients.

摘要

是一种新兴的酵母菌种,也是一种机会致病菌。由于其多重耐药性以及定植和传播能力,它对医疗机构的暴发构成重大风险。在本研究中,我们报告了在中国广西一名儿科骨髓移植患儿中首次检测到 的病例。 从尿液中分离出来,并使用基质辅助激光解吸电离飞行时间(MALDI-TOF)质谱进行鉴定,通过测序确定该分离株属于进化枝I。我们实施了严格的感染控制措施,包括个人防护装备和单间治疗,并对患者体表以及相关医疗和后勤人员、医疗设备和周围环境表面进行定期监测筛查。这些措施旨在有效控制患者体内 的定植,防止其在医院内传播,并确保患者的诊断和治疗质量。

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