Thanh Nguyen Phuong Ngo, Katsume Yumi, Ueda Akiko, Matsuo Seiichiro, Nonoguchi Noriko, Ikewaki Hirotsugu, Mohri Takato, Hoshida Kyoko, Tashiro Mika, Sato Toshiaki, Togashi Ikuko, Soejima Kyoko
Department of Cardiovascular Medicine, Kyorin University School of Medicine, Mitaka, Japan.
Department of Cardiac Electrophysiology and Pacing, Tam Duc Heart Hospital, Ho Chi Minh City, Vietnam.
Heart Rhythm O2. 2024 Oct 9;5(12):910-916. doi: 10.1016/j.hroo.2024.09.021. eCollection 2024 Dec.
Junctional rhythm (JR) frequently occurs during radiofrequency (RF) ablation procedures targeting the slow pathway (SP) for atrioventricular nodal re-entrant tachycardia (AVNRT), signaling successful ablation. Two types of JR have been noticed: typical JR as His activation preceding atrial activation, and atypical JR as atrial activation preceding the His activation. Nevertheless, the origin and characteristics of JR remain incompletely defined.
This study aimed to investigate whether JR induced by RF ablation at the anatomical SP position could reveal preferential conduction in the antegrade vs the retrograde direction.
Consecutive RF ablation procedures targeting the SP for AVNRT were performed in 40 patients. Using electroanatomic mapping, the coronary sinus ostium, His bundle, RF sites, and the distances between these sites and the RF sites (n = 216) were analyzed. We compared the H-A and A-H intervals during AVNRT and JR.
In typical AVNRT, the H-A resembled the H-A with an identical atrial activation sequence, supporting JR conduction to the atrium via a fast pathway. The atypical AVNRT group displayed a significantly shorter A-H than the A-H ( .0001) with identical atrial activation. The JR incidence in patients with both typical and atypical AVNRT showed no correlation with the RF site location.
For patients with typical AVNRT, JR induced by SP ablation preferentially followed the fast pathway. In patients with atypical AVNRT and with retrograde SP conduction, a shorter A-H interval during JR, with the same atrial sequence as that observed during atypical AVNRT, implies retrograde conduction from the SP to the atrium.
房室结折返性心动过速(AVNRT)慢径路(SP)射频消融术中常出现交界性心律(JR),提示消融成功。已发现两种类型的JR:典型JR为希氏束激动先于心房激动,非典型JR为心房激动先于希氏束激动。然而,JR的起源和特征仍未完全明确。
本研究旨在探讨在解剖学SP位置进行射频消融诱导的JR是否能揭示其顺行与逆行方向的优先传导。
对40例因AVNRT行SP射频消融的患者进行连续观察。使用电解剖标测分析冠状窦口、希氏束、射频消融部位以及这些部位与射频消融部位之间的距离(n = 216)。比较AVNRT和JR期间的H - A间期和A - H间期。
在典型AVNRT中,H - A间期与具有相同心房激动顺序的H - A间期相似,支持JR通过快径路传导至心房。非典型AVNRT组在心房激动相同的情况下,A - H间期明显短于A - H间期(P <.0001)。典型和非典型AVNRT患者的JR发生率与射频消融部位无关。
对于典型AVNRT患者,SP消融诱导的JR优先沿快径路传导。对于非典型AVNRT且存在SP逆行传导的患者,JR期间A - H间期较短,且心房顺序与非典型AVNRT期间相同,提示从SP到心房的逆行传导。