Armstrong R B, Vandenakker C B, Laughlin M H
J Appl Physiol (1985). 1985 Mar;58(3):698-701. doi: 10.1152/jappl.1985.58.3.698.
We studied the distribution of blood flow within and among muscles of partially curarized (40-100 micrograms/kg body wt) rats during preexercise and at 1 min of low-speed treadmill exercise (15 m/min). Glycogen loss in the deep red muscles and parts of muscles was significantly reduced in the curarized animals during exercise, indicating the fibers in these muscles were recruited to a lesser extent and/or had lower metabolisms than fibers in the same muscles of control rats. However, elevations in blood flow in the red muscles of the curarized rats were as great or greater than those in the control rats. Thus reduced recruitment and/or metabolism of the deep red muscle fibers of the curarized animals was not accompanied by reduced blood flow. These findings suggest a dissociation between red fiber metabolism and blood flow in the curarized rats during the 1st min of slow treadmill exercise and indicate that release of vasodilator substances or local physical factors associated with muscle fiber activity are not solely responsible for the initial hyperemia during exercise.
我们研究了部分箭毒化（40 - 100微克/千克体重）大鼠在运动前以及低速跑步机运动（15米/分钟）1分钟时，肌肉内部和肌肉之间的血流分布情况。在运动过程中，箭毒化动物深红色肌肉和部分肌肉中的糖原损失显著减少，这表明这些肌肉中的纤维被募集的程度较低和/或代谢率低于对照大鼠相同肌肉中的纤维。然而，箭毒化大鼠红色肌肉中的血流增加幅度与对照大鼠相同或更大。因此，箭毒化动物深红色肌肉纤维募集减少和/或代谢降低并未伴随血流减少。这些发现表明，在慢速跑步机运动的第1分钟，箭毒化大鼠红色纤维代谢与血流之间存在分离，并且表明血管舒张物质的释放或与肌肉纤维活动相关的局部物理因素并非运动期间初始充血的唯一原因。
