Naidu Ramana K, Kapural Leonardo, Li Sean, Tourjé Caitlin, Rutledge Joseph, Dickerson David, Lubenow Timothy R
MarinHealth Spine Institute, a UCSF Affiliate, 2 Bon Air Rd #120, Larkspur, CA, 94939, USA.
Carolinas Pain Institute, Winston-Salem, NC, USA.
Curr Pain Headache Rep. 2025 Jan 13;29(1):25. doi: 10.1007/s11916-024-01318-3.
The purpose of this review is to describe the development and key features of the Prospera™ Spinal Cord Stimulation (SCS) System, as well as the clinical evidence supporting its use. Prospera delivers therapy using a proprietary multiphase stimulation paradigm and is the first SCS system to offer proactive care through automatic, objective, daily, remote device monitoring and remote programming capabilities.
Results from the recently published BENEFIT-02 trial support the short-term safety and efficacy of multiphase stimulation in patients with chronic pain. BENEFIT-03 is an ongoing, multicenter, single-arm study with 24-month follow-up; interim analyses suggest that multiphase therapy is safe and effective and that patients and clinicians have positive experiences with remote device management. Preliminary evidence suggests that the Prospera SCS System represents an opportunity to improve patient care by combining an effective multiphase stimulation paradigm with an efficient proactive care model.
本综述旨在描述Prospera™脊髓刺激（SCS）系统的发展和关键特性，以及支持其应用的临床证据。Prospera采用专有的多阶段刺激模式进行治疗，是首个通过自动、客观、每日远程设备监测和远程编程功能提供主动护理的SCS系统。
最近发表的BENEFIT - 02试验结果支持多阶段刺激对慢性疼痛患者的短期安全性和有效性。BENEFIT - 03是一项正在进行的多中心单臂研究，随访24个月；中期分析表明多阶段治疗安全有效，患者和临床医生对远程设备管理有积极体验。初步证据表明，Prospera SCS系统通过将有效的多阶段刺激模式与高效的主动护理模式相结合，为改善患者护理提供了契机。
