Schulz B O, Baker E, Krebs D, Sellin D
J Cancer Res Clin Oncol. 1985;109(2):152-5. doi: 10.1007/BF00391890.
For 230 patients with common epithelial ovarian cancer, the prognostic impact of age was examined. Statistical analysis was done using proportional hazard models, 3- and 5-year survival rates and median survival of stratified groups, and the Kaplan-Meier mean. Taking the age-adjusted mortality into account, the prognosis of the older patients was significantly worse. This effect depended primarily on early mortality (survival time less than 2 months). A comparative analysis was made of the prognostic factors age, grade, and stage, taking into account the correlation between factors. This analysis showed that, for our series, age was of lesser prognostic significance than grading, and both of these were of much less prognostic importance than staging.
对230例常见上皮性卵巢癌患者,研究了年龄对预后的影响。采用比例风险模型、分层组的3年和5年生存率及中位生存期以及Kaplan-Meier均值进行统计分析。考虑年龄调整后的死亡率,老年患者的预后明显更差。这种影响主要取决于早期死亡率(生存时间少于2个月)。在考虑因素间相关性的情况下,对年龄、分级和分期等预后因素进行了比较分析。该分析表明,对于我们的研究系列,年龄的预后意义小于分级,而这两者的预后重要性均远低于分期。