Ugochukwu Ezinwanne Jane, Edom Jennifer Chinwe, Omotayo Faith Olanrewaju, Amaechi Agatha Adaeze, Obetta Chinedu Benneth, Anosike Chibueze, Isah AbdulMuminu, Ubaka Chukwuemeka Michael
Department of Clinical Pharmacy and Pharmacy Management, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria.
BMC Med Educ. 2025 Jan 14;25(1):63. doi: 10.1186/s12909-025-06651-8.
Individuals often respond differently to medications, giving rise to the field of precision medicine (PM), which focuses on tailoring treatments to individual genetic, environmental, and lifestyle factors. This study examined the level of comfort healthcare professional students have with their knowledge of precision medicine, alongside their attitudes and perceptions toward precision medicine, at a tertiary institution in Nigeria.
A cross-sectional questionnaire-based study was conducted among healthcare professional students (400-600 level) at the University of Nigeria Nsukka between January and March 2024. The data were analyzed via IBM Statistical Product and Service Solutions (SPSS) for Windows version 27. Descriptive analyses (frequency, percentage, mean, and standard deviation) and chi-square tests were used to summarize and compare the variables. Statistical significance was set at p < 0.05.
A total of 431 healthcare professional students participated in this study. Fewer than half (n = 200, 46.4%) were pharmacy students, and the majority were within the age range of 21-25 years (n = 288, 66.8%). Nearly half (n = 206, 47.8%) reported having information about precision medicine from the internet, and the majority (n = 341, 79.1%) expressed having an interest in a career involving research in precision medicine. More than half of the students (n = 240, 55.7%) were comfortable with their knowledge of precision medicine and had favourable attitudes (n = 236, 54.8%). Additionally, more than half had positive perceptions of ethical concerns (n = 216, 50.1%) and education in precision medicine (n = 239, 55.5%). Gender, age, department, level of study, awareness of PM, and interest in a career involving research were significantly associated with students' knowledge, attitudes, and perceptions of precision medicine (p < 0.001).
Healthcare professional students were comfortable with their knowledge of PM and, in addition, had favourable attitudes and positive perceptions toward the use of precision medicine.
个体对药物的反应往往不同，由此产生了精准医学（PM）领域，该领域专注于根据个体的基因、环境和生活方式因素定制治疗方案。本研究调查了尼日利亚一所高等院校中，医疗专业学生对精准医学知识的熟悉程度，以及他们对精准医学的态度和看法。
2024年1月至3月期间，在尼日利亚大学恩苏卡分校对医疗专业学生（400 - 600年级）开展了一项基于问卷调查的横断面研究。数据通过IBM统计产品与服务解决方案（SPSS）Windows版27进行分析。采用描述性分析（频率、百分比、均值和标准差）和卡方检验来总结和比较变量。设定统计学显著性水平为p < 0.05。
共有431名医疗专业学生参与了本研究。不到一半（n = 200，46.4%）是药学专业学生，大多数学生年龄在21 - 25岁之间（n = 288，66.8%）。近一半（n = 206，47.8%）的学生表示从互联网上了解到有关精准医学的信息，大多数（n = 341，79.1%）表示对从事精准医学研究的职业感兴趣。超过一半的学生（n = 240，55.7%）对自己的精准医学知识感到满意，并且态度积极（n = 236，54.8%）。此外，超过一半的学生对伦理问题（n = 216，50.1%）和精准医学教育（n = 239，55.5%）有积极的看法。性别、年龄、专业、学习水平、对精准医学的认知以及对从事研究职业的兴趣与学生对精准医学的知识、态度和看法显著相关（p < 0.001）。
医疗专业学生对自己的精准医学知识感到满意，并且对精准医学的应用态度积极、看法正面。
