Chen Weibu, Chen Xueyan
Laboratory Department, Shenzhen People's Hospital, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, Guangdong, PR China.
Clinical Laboratory, Department of Clinical Laboratory, Shenzhen Longhua District People's Hospital, Shenzhen, PR China.
IDCases. 2024 Dec 16;39:e02136. doi: 10.1016/j.idcr.2024.e02136. eCollection 2025.
HIV infection frequently affects multiple systems, with hematological manifestations being the most prevalent. In some cases, cryptococcosis serves as the initial manifestation and a cause of infection involving HIV-positive patients. This case report describes a patient with thrombocytopenia who incidentally discovered infiltrating the bone marrow upon bone marrow smear examination, highlighting that examining bone marrow is essential in diagnosing pancytopenia resulting from opportunistic fungal infections like cryptococcosis, especially in individuals with compromised immune systems.
HIV感染常累及多个系统,血液学表现最为常见。在某些情况下,隐球菌病是HIV阳性患者感染的初始表现及病因。本病例报告描述了一名血小板减少症患者,其在骨髓涂片检查时偶然发现骨髓有浸润,强调了骨髓检查对于诊断由隐球菌病等机会性真菌感染导致的全血细胞减少至关重要,尤其是在免疫系统受损的个体中。