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肺包虫囊肿误诊为肺癌。

Pulmonary hydatid cyst misdiagnosed as lung cancer.

作者信息

Messaoudi Houssem, Ben Ismail Imen, Ragmoun Wafa, Lajmi Mokhles, Zayène Bochra, Mejri Islam, Hachicha Saber

机构信息

Department of Cardiac and Thoracic Surgery, The Military Hospital of Instruction of Tunis, Tunisia.

Department of General Surgery, Traumatology and Severe Burns Center Ben Arous, Tunisia.

出版信息

IDCases. 2024 Dec 16;39:e02133. doi: 10.1016/j.idcr.2024.e02133. eCollection 2025.

Abstract

Hydatid disease is endemic in Tunisia. Whereas uncomplicated pulmonary hydatid cysts are easily diagnosed on radiological findings, complicated and atypical forms may be misdiagnosed and confused with other pulmonary lesions, mainly lung malignancies. We report a case of a 47-year-old woman, who presented with a 3-month history of hemoptysis. Physical examination was normal. Chest x-ray and CT scan of the chest revealed a mass with speculated margins and central necrosis, located in the apical segment of the right lower lobe moderately contrast-enhanced. The scan guided biopsy showed inflammatory pulmonary parenchyma with no signs of malignancy. Fiberoptic bronchoscopy revealed significant bleeding from the superior segmental bronchus of right lower lobe. Pathology examination of the bronchial aspiration revealed a suggestive aspect of malignant cells. Regarding those findings, lung carcinoma was highly suspected and the importance of hemoptysis motivated an urgent hemostasis lobectomy. The patient underwent a right lower lobectomy with radical lymph node dissection via a right posterolateral thoracotomy. Histological examination showed a laminated membrane lined by a proligerous membrane made up of a layer of eosinophilic cells confirming the diagnosis of pulmonary hydatid cyst. It should be kept in mind that pulmonary hydatid disease can clinically, radiologically mimic lung cancer. Exceptionally, even cytology can lead to a diagnosis pitfall.

摘要

包虫病在突尼斯呈地方性流行。单纯性肺包虫囊肿通过影像学检查很容易诊断,而复杂性和非典型性包虫病可能会被误诊,并与其他肺部病变(主要是肺癌)相混淆。我们报告了一例47岁女性患者,有3个月咯血病史。体格检查正常。胸部X线和胸部CT扫描显示右肺下叶尖段有一肿块,边缘呈分叶状,中央坏死,增强扫描呈中度强化。扫描引导下活检显示为炎性肺实质,无恶性征象。纤维支气管镜检查显示右下叶上段支气管有大量出血。支气管吸出物的病理检查显示有恶性细胞的可疑表现。鉴于这些发现,高度怀疑为肺癌,且咯血的严重性促使进行紧急止血性肺叶切除术。患者通过右后外侧开胸手术接受了右下叶切除术及根治性淋巴结清扫术。组织学检查显示有一层由生发层膜衬里的板层膜,生发层膜由一层嗜酸性细胞组成,确诊为肺包虫囊肿。应牢记,肺包虫病在临床和影像学上可酷似肺癌。甚至在极少数情况下,细胞学检查也可能导致诊断失误。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3092/11729004/9abac528677c/gr1.jpg

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