Alnakhli Abdulaziz S, AlShaikh Kawther, Al Saud Ahad, Rahim Owais
Emergency Medicine, King Khalid University Hospital, Riyadh, SAU.
Cardiology, King Khalid University Hospital, Riyadh, SAU.
Cureus. 2024 Dec 14;16(12):e75692. doi: 10.7759/cureus.75692. eCollection 2024 Dec.
Troponin is a highly specific biomarker for myocardial injury. It plays a critical role in the diagnosis of acute coronary syndrome (ACS). However, elevated troponin levels are not exclusively due to cardiac ischemia and may be observed in many non-cardiac conditions, including inflammatory myopathies. These scenarios present significant diagnostic challenges, particularly when clinical symptoms and ECG (electrocardiogram) findings do not align with cardiac pathology. Recognizing alternative etiologies, such as autoimmune diseases, is essential to prevent unnecessary investigations and ensure appropriate management. This report emphasizes the importance of a comprehensive diagnostic approach to identify non-cardiac causes of high troponin levels and to avoid misdiagnosing patients.
肌钙蛋白是心肌损伤的一种高度特异性生物标志物。它在急性冠状动脉综合征（ACS）的诊断中起着关键作用。然而，肌钙蛋白水平升高并非仅由心肌缺血引起，在许多非心脏疾病中也可能观察到，包括炎症性肌病。这些情况带来了重大的诊断挑战，尤其是当临床症状和心电图（ECG）结果与心脏病理不相符时。认识到自身免疫性疾病等其他病因对于避免不必要的检查和确保适当的治疗至关重要。本报告强调了采用全面诊断方法来识别肌钙蛋白水平升高的非心脏原因并避免误诊患者的重要性。
