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美国成年人中薄荷醇模拟香烟的认知与使用情况

Knowledge and Use of Menthol-Mimicking Cigarettes Among Adults in the US.

作者信息

Choi Kelvin, Hamilton-Moseley Kristen R, Phan Lilianna, Azeem Ayesha, Jewett Bambi, Zarei Kasra, Hacker Kiana

机构信息

Division of Intramural Research, National Institute on Minority Health and Health Disparities, Bethesda, Maryland.

Department of Community Health and Prevention, Dornsife School of Public Health and Division of Graduate Nursing, College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania.

出版信息

JAMA Netw Open. 2025 Jan 2;8(1):e2454608. doi: 10.1001/jamanetworkopen.2024.54608.

DOI:10.1001/jamanetworkopen.2024.54608
PMID:39808430
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11733694/
Abstract

IMPORTANCE

Cigarette companies have been introducing synthetic cooling agent menthol-mimicking cigarettes into the US marketplace as menthol cigarette bans are implemented. These cigarettes may reduce the public health benefits of menthol cigarette bans.

OBJECTIVE

To examine the epidemiology of the use of synthetic cooling agent menthol-mimicking cigarettes among adults in the US.

DESIGN, SETTING, AND PARTICIPANTS: This population-based cross-sectional survey study of adults in the US (≥21 years) with oversampling of Asian, American Indian or Alaska Native, Black or African American, and Hispanic or Latino peoples was conducted from March to May 2024. Participants were recruited from an online panel using a sample-matching approach to achieve national representation. Data were weighted to be nationally representative. Descriptive statistics were used to summarize the population characteristics. Weighted prevalence of awareness of, ever use (among those aware), current use (among ever used), susceptibility (among noncurrent use), and likely to switch to synthetic cooling agent menthol-mimicking cigarettes were estimated overall and by covariate. Sequential weighted logistic regression models were used to estimate the associations between covariates and synthetic cooling agent menthol-mimicking-related outcomes (awareness, ever use, current use, susceptibility). Statistical analysis was performed from July to September 2024.

EXPOSURES

Demographics, state menthol cigarette ban, cigarette smoking, and disclosure of synthetic cooling agent.

MAIN OUTCOMES AND MEASURES

Awareness of, susceptibility to, ever and currently using synthetic cooling agent menthol-mimicking cigarettes and intention to switch to these cigarettes if a nationwide menthol cigarette ban were enacted.

RESULTS

The study population included 3200 US adults (47.4% men; 0.8% American Indian or Alaska Native, 5.9% Asian, 12.0% Black or African American, 16.0% Hispanic or Latino, 63.6% White, and 1.9% other race; 34.8% with a college degree; and 36.7% with annual household income of ≥$75 000). Overall, 29.1% (95% CI, 27.0%-31.1%) of US adults were aware of synthetic cooling agent menthol-mimicking cigarettes, 36.9% (95% CI, 33.1%-40.8%) of those aware ever used these cigarettes, 24.7% (95% CI, 20.1%-29.3%) of those who ever used reported currently using these cigarettes, and 37.5% (95% CI, 33.4%-41.6%) of those not currently using were susceptible to using them. Black or African American (vs White), men (vs women), adults aged 60 years or younger (vs adults aged ≥61 years), adults who used menthol and nonmenthol cigarettes (vs adults who did not smoke cigarettes), and those who lived in states with a menthol cigarette ban (vs those who lived in states with no ban) had higher odds of awareness, ever use, current use, and/or susceptibility to these cigarettes. Considering a national menthol cigarette ban, 50.8% (95% CI, 42.8%-58.7%) of adults who smoked menthol cigarettes and were aware of menthol-mimicking cigarettes with a synthetic cooling agent reported likely to switch to these cigarettes. Ever using these cigarettes was associated with the likelihood of switching (adjusted odds ratio, 2.61 [95% CI, 1.20-5.68]).

CONCLUSIONS AND RELEVANCE

In this survey study of US adults, a substantial proportion were aware of and had already experimented with synthetic cooling agent menthol-mimicking cigarettes. These products may serve as a substitute for menthol cigarettes and reduce the public health benefits of a menthol cigarette ban in promoting smoking cessation.

摘要

重要性

随着薄荷醇香烟禁令的实施,烟草公司一直在将含有合成冷却剂、模仿薄荷醇的香烟引入美国市场。这些香烟可能会降低薄荷醇香烟禁令带来的公共卫生效益。

目的

研究美国成年人中使用含有合成冷却剂、模仿薄荷醇香烟的流行病学情况。

设计、背景和参与者:这是一项基于人群的横断面调查研究,于2024年3月至5月对美国21岁及以上成年人进行,对亚洲、美洲印第安人或阿拉斯加原住民、黑人或非裔美国人以及西班牙裔或拉丁裔人群进行了过度抽样。参与者通过样本匹配方法从在线小组中招募,以实现全国代表性。数据进行加权处理以具有全国代表性。使用描述性统计来总结人群特征。总体以及按协变量估计了对含有合成冷却剂、模仿薄荷醇香烟的知晓率、曾经使用过(在知晓者中)、当前使用(在曾经使用者中)、易感性(在当前未使用者中)以及可能转向使用含有合成冷却剂、模仿薄荷醇香烟的加权患病率。使用序贯加权逻辑回归模型来估计协变量与含有合成冷却剂、模仿薄荷醇香烟相关结果(知晓、曾经使用、当前使用、易感性)之间的关联。统计分析于2024年7月至9月进行。

暴露因素

人口统计学特征、州薄荷醇香烟禁令、吸烟情况以及合成冷却剂的披露情况。

主要结局和测量指标

对含有合成冷却剂、模仿薄荷醇香烟的知晓、易感性、曾经和当前使用情况,以及如果全国实施薄荷醇香烟禁令是否打算转向使用这些香烟。

结果

研究人群包括3200名美国成年人(47.4%为男性;0.8%为美洲印第安人或阿拉斯加原住民,5.9%为亚洲人,12.0%为黑人或非裔美国人,16.0%为西班牙裔或拉丁裔,63.6%为白人,1.9%为其他种族;34.8%拥有大学学位;36.7%家庭年收入≥75000美元)。总体而言,29.1%(95%CI,27.0%-31.1%)的美国成年人知晓含有合成冷却剂、模仿薄荷醇的香烟,知晓者中有36.9%(95%CI,33.1%-40.8%)曾经使用过这些香烟,曾经使用者中有24.7%(95%CI,20.1%-29.3%)报告当前正在使用这些香烟,当前未使用者中有37.5%(95%CI,33.4%-41.6%)易使用这些香烟。黑人或非裔美国人(与白人相比)、男性(与女性相比)、60岁及以下成年人(与61岁及以上成年人相比)、使用薄荷醇和非薄荷醇香烟的成年人(与不吸烟的成年人相比)以及居住在有薄荷醇香烟禁令州的人(与居住在无禁令州的人相比)对这些香烟的知晓、曾经使用、当前使用和/或易感性几率更高。考虑到全国性的薄荷醇香烟禁令,吸食薄荷醇香烟且知晓含有合成冷却剂、模仿薄荷醇香烟的成年人中有50.8%(95%CI,42.8%-58.7%)报告可能会转向使用这些香烟。曾经使用过这些香烟与转向使用的可能性相关(调整后的优势比为2.61[95%CI,1.20-5.68])。

结论和相关性

在这项针对美国成年人的调查研究中,很大一部分人知晓并已经尝试过含有合成冷却剂、模仿薄荷醇的香烟。这些产品可能会替代薄荷醇香烟,并降低薄荷醇香烟禁令在促进戒烟方面的公共卫生效益。

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本文引用的文献

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Sociodemographic and Temporal Differences in Menthol Cigarette Use Among US Adults Who Smoke, 1999-2018.1999-2018 年美国成年吸烟人群中薄荷醇卷烟使用的社会人口学和时间差异。
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Effects of 'Ice' flavoured e-cigarettes with synthetic cooling agent WS-23 or menthol on user-reported appeal and sensory attributes.含合成冷却剂WS-23或薄荷醇的“冰”味电子烟对用户报告的吸引力和感官属性的影响。
Tob Control. 2025 Apr 1;34(2):175-182. doi: 10.1136/tc-2023-058125.
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Synthetic Cooling Agent and Other Flavor Additives in "Non-Menthol" Cigarettes Marketed in California and Massachusetts After Menthol Cigarette Bans.在薄荷醇香烟禁令实施后,加利福尼亚州和马萨诸塞州销售的“非薄荷醇”香烟中的合成冷却剂和其他调味添加剂。
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Still 'Cool': tobacco industry responds to state-wide menthol ban with synthetic coolants.依然“清凉”:烟草行业用合成冷却剂应对全州薄荷醇禁令。
Tob Control. 2025 Apr 1;34(2):254-258. doi: 10.1136/tc-2023-058149.
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Proliferation of 'non-menthol' cigarettes amid a state-wide flavour ban.在全州范围内实施口味禁令的情况下,“非薄荷醇”香烟的销量激增。
Tob Control. 2025 Jan 2;34(1):135-137. doi: 10.1136/tc-2023-058074.
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Synthetic cooling agent in oral nicotine pouch products marketed as 'Flavour-Ban Approved'.作为“口味禁令批准”销售的口服尼古丁小袋产品中的合成冷却剂。
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Menthol Cigarette Smoking Trends among United States Adults, 2003-2019.美国成年人薄荷醇卷烟吸烟趋势,2003-2019 年。
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Ice flavours and non-menthol synthetic cooling agents in e-cigarette products: a review.电子烟产品中的冰味剂和非薄荷醇合成冷却剂:综述。
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10
What more evidence is needed? Remove menthol cigarettes from the marketplace-now.还需要更多什么证据呢?现在就把薄荷醇香烟从市场上移除。
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