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腹部大手术后发生杓状软骨脱位的危险因素:一项回顾性研究。

Risk factors for the occurrence of arytenoid dislocation after major abdominal surgery: A retrospective study.

作者信息

Chen Mo, Yu Tingting, Cui Xiangyan, Wang Xin

机构信息

Department of Otolaryngology Head and Neck Surgery, The First Hospital of Jilin University, Changchun, Jilin, China.

出版信息

Medicine (Baltimore). 2024 Nov 22;103(47):e40593. doi: 10.1097/MD.0000000000040593.

DOI:10.1097/MD.0000000000040593
PMID:39809151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11596634/
Abstract

The incidence of arytenoid dislocation in abdominal surgery is relatively high, the cause is unknown, and it has not received sufficient attention. To identify the risk factors of arytenoid dislocation after abdominal surgery, and to establish a clinical prediction model based on relevant clinicopathological characteristics. We retrospectively collected the clinical data of 50 patients with arytenoid dislocation (AD) and 200 patients without AD after abdominal surgery with general anesthetic tracheal intubation in our Hospital from January 2013 to December 2019. General information about the patients was collected. Univariate analysis of the factors was performed, and indicators that were statistically significant were included in multivariate logistic regression analyses to identify the relationship between clinicopathological characteristics and arytenoid dislocation. Meanwhile, a clinical prediction model was established. Multivariate logistic regression analyses showed that age, surgical methods, operative time and gastric tube were dependent predictive factors of AD after abdominal surgery. A clinical prediction model was constructed, and the AUC of the ROC curve was 0.88 (95%CI: 0.83-0.94). The calibration plot shows that the prediction curve was close to the ideal curve. Patients undergoing abdominal surgery with general anesthesia exhibit a significantly higher incidence of AD due to a combination of factors. Clinicopathological features can be used as an independent predictor of risk in patients with AD, and a clinical model has been developed that is a good predictor of AD.

摘要

腹部手术中杓状软骨脱位的发生率相对较高,病因不明,且尚未得到足够重视。旨在识别腹部手术后杓状软骨脱位的危险因素,并基于相关临床病理特征建立临床预测模型。我们回顾性收集了2013年1月至2019年12月在我院接受全身麻醉气管插管腹部手术后发生杓状软骨脱位(AD)的50例患者和未发生AD的200例患者的临床资料。收集患者的一般信息。对各因素进行单因素分析,将具有统计学意义的指标纳入多因素logistic回归分析,以确定临床病理特征与杓状软骨脱位之间的关系。同时,建立临床预测模型。多因素logistic回归分析显示,年龄、手术方式、手术时间和胃管是腹部手术后AD的独立预测因素。构建了临床预测模型,ROC曲线的AUC为0.88(95%CI:0.83 - 0.94)。校准图显示预测曲线接近理想曲线。由于多种因素的综合作用,接受全身麻醉腹部手术的患者AD发生率显著更高。临床病理特征可作为AD患者风险的独立预测指标,且已开发出一种临床模型,对AD具有良好的预测能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/96894894fef1/medi-103-e40593-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/fa1551dbb7c2/medi-103-e40593-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/05b07b87da1b/medi-103-e40593-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/b3332929a215/medi-103-e40593-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/39cc623fe309/medi-103-e40593-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/96894894fef1/medi-103-e40593-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/fa1551dbb7c2/medi-103-e40593-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/05b07b87da1b/medi-103-e40593-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/b3332929a215/medi-103-e40593-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/39cc623fe309/medi-103-e40593-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b66/11596634/96894894fef1/medi-103-e40593-g005.jpg

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本文引用的文献

1
High prevalence of postoperative arytenoid dislocation in patients undergoing liver transplantation: A case-control study.肝移植术后杓状软骨脱位的高发率:一项病例对照研究。
Medicine (Baltimore). 2023 Aug 25;102(34):e34771. doi: 10.1097/MD.0000000000034771.
2
Risk factors of arytenoid dislocation after endotracheal intubation: A propensity-matched analysis.气管插管后杓状软骨脱位的危险因素:一项倾向匹配分析。
Laryngoscope Investig Otolaryngol. 2022 Nov 24;7(6):1979-1986. doi: 10.1002/lio2.977. eCollection 2022 Dec.
3
Application of 4D-CT Scanning in Differential Diagnosis of Arytenoid Subluxation and Vocal Fold Paralysis.
4D-CT 扫描在诊断杓状软骨半脱位和声门运动不能中的应用。
J Voice. 2022 Nov;36(6):859-867. doi: 10.1016/j.jvoice.2020.09.027. Epub 2020 Oct 16.
4
Clinical characteristics of arytenoid dislocation in patients undergoing bariatric/metabolic surgery: A STROBE-complaint retrospective study.肥胖/代谢手术患者杓状软骨脱位的临床特征:一项遵循STROBE标准的回顾性研究。
Medicine (Baltimore). 2019 Apr;98(17):e15318. doi: 10.1097/MD.0000000000015318.
5
Association between the use of a stylet in endotracheal intubation and postoperative arytenoid dislocation: a case-control study.气管插管时使用管芯与术后杓状软骨脱位之间的关联:一项病例对照研究。
BMC Anesthesiol. 2018 May 31;18(1):59. doi: 10.1186/s12871-018-0521-9.
6
[The diagnostic value of laryngeal electromyography in vocal fold paralysis and arytenoid dislocation].[喉肌电图在声带麻痹及杓状软骨脱位中的诊断价值]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Mar;32(6):420-423. doi: 10.13201/j.issn.1001-1781.2018.06.006.
7
BMI May Be the Risk Factor for Arytenoid Dislocation Caused by Endotracheal Intubation: A Retrospective Case-Control Study.体重指数可能是气管插管致杓状软骨脱位的危险因素:一项回顾性病例对照研究。
J Voice. 2018 Mar;32(2):221-225. doi: 10.1016/j.jvoice.2017.05.010. Epub 2017 Jun 7.
8
The appropriate time for closed reduction using local anesthesia in arytenoid dislocation caused by intubation: a clinical research.局部麻醉下闭合复位治疗气管插管致杓状软骨脱位的适宜时机:一项临床研究
Acta Otolaryngol. 2017 Mar;137(3):331-336. doi: 10.1080/00016489.2016.1230276. Epub 2016 Sep 22.
9
Large-bore calibrating orogastric tube and arytenoid dislocation: a retrospective study.大口径校准口胃管与杓状软骨脱位:一项回顾性研究
Br J Anaesth. 2016 Feb;116(2):296-8. doi: 10.1093/bja/aev463.
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[Modified closed reduction for the arytenoid cartilage dislocation].[改良闭合复位治疗杓状软骨脱位]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jun;48(6):450-4.