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一名患有原发性甲状旁腺功能亢进症的老年患者的股骨颈骨折:病例报告。

Femoral neck fracture in a senile patient with primary hyperparathyroidism: A case report.

作者信息

Zhu Hong-Xia, Fu Lei, Xie Yu, Yuan Xiao, Chen Sheng-Tao, Xie Lun-Li

机构信息

Department of Traumatic Orthopedics, Hunan University of Medicine General Hospital, Huaihua, China.

Department of Joint and Hand Orthopedics, Hunan University of Medicine General Hospital, Huaihua, China.

出版信息

Medicine (Baltimore). 2024 Nov 22;103(47):e40277. doi: 10.1097/MD.0000000000040277.

Abstract

RATIONALE

As a rare cause of femoral neck fracture, usually, hyperparathyroidism is missed diagnosed by orthopedist. Patient can present with various disappearance of clinical manifestations. Primary hyperparathyroidism in senile male population is commonly an asymptomatic disorder discovered incidentally through routine lab testing. Here, this study reports a case of femoral neck fracture in a senile patient with primary hyperparathyroidism.

PATIENTS CONCERNS

A 70-year-old male patient with a known right femoral neck fracture associated with primary hyperparathyroidism.

DIAGNOSES

A neck ultrasound (US) and computed tomography revealed a solid mass below the right lobe of the thyroid. X-ray plain and computed tomography confirmed right femoral neck fracture and multiple bone lesions. The routine lab testing showed hypercalcemia and hyperkalemia.

INTERVENTIONS

Before undergoing total hip arthroplasty surgery, patient was temporarily treated with hydration, diuretics, and calcitonin. Besides, the patient underwent parathyroidectomy of the enlarged parathyroid gland. Oral calcium preparations were routinely used for prevention of hypocalcemia.

OUTCOMES

After completing all surgery, the patient was discharged without any complications including hypercalcemia and hyperkalemia.

LESSONS

Femoral neck fracture associated with primary hyperparathyroidism is a rare presentation. This case highlights that hypercalcemia and multiple osteopathy should be considered in the differential diagnosis in patients with pathological fracture caused by micro-traumatic injury.

摘要

理论依据

作为股骨颈骨折的罕见病因,甲状旁腺功能亢进症通常易被骨科医生漏诊。患者可能出现各种临床表现消失的情况。老年男性人群中的原发性甲状旁腺功能亢进症通常是通过常规实验室检查偶然发现的无症状疾病。在此,本研究报告一例患有原发性甲状旁腺功能亢进症的老年患者股骨颈骨折的病例。

患者情况

一名70岁男性患者,已知患有与原发性甲状旁腺功能亢进症相关的右侧股骨颈骨折。

诊断

颈部超声(US)和计算机断层扫描显示甲状腺右叶下方有一个实性肿块。X线平片和计算机断层扫描证实右侧股骨颈骨折和多处骨质病变。常规实验室检查显示高钙血症和高钾血症。

干预措施

在进行全髋关节置换手术前,患者接受了补液、利尿剂和降钙素的临时治疗。此外,患者接受了肿大甲状旁腺的甲状旁腺切除术。常规使用口服钙剂预防低钙血症。

结果

完成所有手术后,患者出院,未出现包括高钙血症和高钾血症在内的任何并发症。

经验教训

与原发性甲状旁腺功能亢进症相关的股骨颈骨折是一种罕见的表现。该病例强调,对于微创伤性损伤所致病理性骨折的患者,鉴别诊断时应考虑高钙血症和多发性骨病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9918/11596578/e9ecc0198d64/medi-103-e40277-g001.jpg

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