Ratnayake Aneeka, Tong Yao, Reynolds Zahra, Chamut Steffany, Quach Lien T, Mbabazi Phoebe, Sagar Shruti, Maling Samuel, North Crystal M, Passell Eliza, Yoo-Jeong Moka, Tsai Alexander C, Paul Robert, Ritchie Christine S, Seeley Janet, Hoeppner Susanne S, Atwiine Flavia, Tindimwebwa Edna, Okello Samson, Nakasujja Noeline, Saylor Deanna, Greene Meredith L, Asiimwe Stephen, Tanner Jeremy A, Siedner Mark J, Olivieri-Mui Brianne
The Roux Institute at Northeastern University, USA.
Medical Practice Evaluation Center, Mongan Institute, Massachusetts General Hospital, USA.
J Aging Health. 2025 Jan 14:8982643251314064. doi: 10.1177/08982643251314064.
Physical Activity (PA) and its links to frailty, quality of life (QoL), and other comorbidities in older Ugandans living with HIV remain under-explored.
We analyzed data from three annual assessments of older people living with HIV (PLWH) and age- and sex-similar people not living with HIV (PnLWH). We fitted linear generalized estimating equations (GEE) regression models to estimate the correlates of PA, including demographics, frailty, QoL, HIV, and other comorbidities.
We enrolled 297 PLWH and 302 PnLWH. Older age (b = -157.34, 95% CI [-222.84, -91.83]), living with HIV (b = -979.88 [95% CI: -1878.48, -81.28]), frailty (b = -3011.14 [95% CI: -4665.84, -1356.45]), and comorbidities (b = -2501.75 [95% CI: -3357.44, -1646.07]) were associated with lower overall PA. Higher general QoL (b = 89.96 [95% CI: 40.99, 138.94]) was associated with higher PA.
PA interventions may support wellbeing of older people in the region, and tailored interventions should be explored.
身体活动(PA)及其与乌干达老年HIV感染者的衰弱、生活质量(QoL)和其他合并症之间的联系仍未得到充分研究。
我们分析了对老年HIV感染者(PLWH)以及年龄和性别匹配的非HIV感染者(PnLWH)进行的三次年度评估数据。我们拟合了线性广义估计方程(GEE)回归模型,以估计PA的相关因素,包括人口统计学、衰弱、QoL、HIV和其他合并症。
我们纳入了297名PLWH和302名PnLWH。年龄较大(b = -157.34,95%CI[-222.84,-91.83])、感染HIV(b = -979.88[95%CI:-1878.48,-81.28])、衰弱(b = -3011.14[95%CI:-4665.84,-1356.45])和合并症(b = -2501.75[95%CI:-3357.44,-1646.07])与较低的总体PA相关。较高的总体QoL(b = 89.96[95%CI:40.99,138.94])与较高的PA相关。
PA干预可能有助于该地区老年人的健康,应探索针对性的干预措施。