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德里婴儿的染色体异态性。III. 1号、9号和16号染色体C带倒位异态性的定性分析。

Chromosomal heteromorphisms in Delhi infants. III. Qualitative analysis of C-band inversion heteromorphisms of chromosomes 1, 9, and 16.

作者信息

Potluri V R, Singh I P, Bhasin M K

出版信息

J Hered. 1985 Jan-Feb;76(1):55-8. doi: 10.1093/oxfordjournals.jhered.a110018.

Abstract

Qualitative analysis of C-band heteromorphisms was carried out in 200 infants (100 males and 100 females) in Delhi, India. Partial inversions minor and half inversions were observed as modal levels for chromosomes 1 and 9 in both sexes. No chromosome 16 with a C-band inversion was observed in the present investigation. A significantly higher incidence of percent inversions for chromosomes 1 and 9 was observed in males than in females. The frequency of heterozygous inversion level combinations for chromosome pairs 1 and 9 were remarkably higher than homozygous combinations both in males and females. Our results are compared with the other reported studies, and the possible role of these heteromorphisms in ethnic/racial variation and in developmental disturbances are discussed.

摘要

对印度德里的200名婴儿(100名男性和100名女性)进行了C带异态性的定性分析。在男女两性中,均观察到1号和9号染色体的部分小倒位和半倒位为模式水平。在本研究中未观察到16号染色体有C带倒位。观察到男性1号和9号染色体的倒位百分比发生率显著高于女性。在男性和女性中,1号和9号染色体对的杂合倒位水平组合频率均显著高于纯合组合。我们将结果与其他已报道的研究进行了比较,并讨论了这些异态性在种族/民族差异和发育障碍中的可能作用。

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