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Clinical prediction models to predict the risk of multiple binary outcomes: a comparison of approaches.预测多种二元结局风险的临床预测模型:方法比较
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Joint modeling of correlated binary outcomes: The case of contraceptive use and HIV knowledge in Bangladesh.相关二元结局的联合建模:以孟加拉国的避孕措施使用情况和艾滋病知识为例。
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使用多元逻辑回归对相关二元结局进行联合建模:斯里兰卡的避孕与艾滋病知识

Joint modeling of correlated binary outcomes using multivariate logistic regression: contraception and HIV knowledge in Sri Lanka.

作者信息

Wijesekara N M, Withanage N, Abeynayake N R

机构信息

Department of Economics and Statistics, Sabaragamuwa University of Sri Lanka, Belihuloya, Sri Lanka.

Department of Statistics, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.

出版信息

J Appl Stat. 2024 Jun 7;52(1):208-220. doi: 10.1080/02664763.2024.2363399. eCollection 2025.

DOI:10.1080/02664763.2024.2363399
PMID:39811086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11727058/
Abstract

Reproductive health significantly contributes to the overall well-being and social welfare of women. Within the spectrum of modern and traditional contraceptive methods in use, condoms have been strongly advocated by numerous HIV programs as a primary means of preventing HIV infection in Sri Lanka. Given the intrinsic relationship between contraceptive utilization and HIV awareness, our study aims to concurrently analyze the patterns of contraceptive usage and HIV knowledge, while accounting for their potential correlation. In this study, we introduced the application of the Gumbel type II distribution to effectively capture the interdependence of these joint probabilities, accounting for various covariates. The outcome of simulation studies demonstrated the superior performance of the integrated joint model, in comparison to the separate univariate models. Our findings highlighted several noteworthy risk factors associated with both contraceptive usage and HIV prevention knowledge. These included variables such as residence, level of education, wealth quintile, husband's education level, number of children, engagement with the newspapers, television viewership, and mobile phone usage. The Result indicates a positive association between the adoption of contraception and the awareness of HIV prevention measures, suggesting that individuals who actively embrace contraception are more likely to possess knowledge about preventing HIV transmission.

摘要

生殖健康对女性的整体福祉和社会福利有着重大贡献。在现有的现代和传统避孕方法范围内,避孕套已被众多艾滋病防治项目大力倡导为斯里兰卡预防艾滋病毒感染的主要手段。鉴于避孕措施的使用与艾滋病毒知晓率之间的内在关系,我们的研究旨在同时分析避孕方法的使用模式和艾滋病毒知识,并考虑它们之间的潜在相关性。在本研究中,我们引入了冈贝尔II型分布的应用,以有效捕捉这些联合概率的相互依存关系,并考虑各种协变量。模拟研究的结果表明,与单独的单变量模型相比,综合联合模型具有更优的性能。我们的研究结果突出了与避孕措施使用和艾滋病毒预防知识相关的几个值得注意的风险因素。这些因素包括居住地点、教育水平、财富五分位数、丈夫的教育水平、子女数量、阅读报纸的情况、电视收视率以及手机使用情况。结果表明,采取避孕措施与艾滋病毒预防措施的知晓率之间存在正相关,这表明积极采取避孕措施的个体更有可能具备预防艾滋病毒传播的知识。