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真皮填充剂注射后唇部黑色素沉着：第二例报告及文献综述

Lip Melanosis Postdermal Filler Injection: Second Case Report and Literature Review.

作者信息

Altariqi Abdulrahman Abdullah, Bin Mubayrik Azizah Fahad

机构信息

College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

Division of Oral Medicine, Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

出版信息

Case Rep Dent. 2025 Jan 7;2025:4265486. doi: 10.1155/crid/4265486. eCollection 2025.

DOI:10.1155/crid/4265486
PMID:39811795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11732275/
Abstract

Oral pigmentation can arise from various factors, including physiological and pathological, or as a manifestation of an underlying systemic disease. We present an atypical case of dermal filler-related complication, in which clinical lip pigmentation was observed. This condition can pose a diagnostic challenge in accurately identifying its cause.

摘要

口腔色素沉着可由多种因素引起，包括生理性和病理性因素，或作为潜在全身性疾病的一种表现。我们报告一例与真皮填充剂相关并发症的非典型病例，其中观察到临床唇部色素沉着。这种情况在准确识别其病因方面可能构成诊断挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/33e81b13e73f/CRID2025-4265486.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/477dd965b58e/CRID2025-4265486.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/ab5d788dcbbf/CRID2025-4265486.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/d379a52ae399/CRID2025-4265486.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/33e81b13e73f/CRID2025-4265486.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/477dd965b58e/CRID2025-4265486.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/ab5d788dcbbf/CRID2025-4265486.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/d379a52ae399/CRID2025-4265486.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebe4/11732275/33e81b13e73f/CRID2025-4265486.004.jpg

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本文引用的文献

1
Global prevalence of oral pigmentation and its related factors: a systematic review and meta-analysis.全球口腔色素沉着的患病率及其相关因素：系统评价和荟萃分析。
J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):e411-e424. doi: 10.1016/j.jormas.2022.01.009. Epub 2022 Jan 20.
2
Nonvascular Complications of Injectable Fillers-Prevention and Management.可注射填充剂的非血管并发症——预防与管理
Indian J Plast Surg. 2020 Dec;53(3):335-343. doi: 10.1055/s-0040-1721872. Epub 2020 Dec 24.
3
Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa.
黑色与棕色：口腔黏膜的非肿瘤性色素沉着
Head Neck Pathol. 2019 Mar;13(1):47-55. doi: 10.1007/s12105-018-0980-9. Epub 2019 Jan 22.
4
Oral melanoma and other pigmentations: when to biopsy?口腔黑色素瘤和其他色素沉着：何时进行活检？
J Eur Acad Dermatol Venereol. 2018 Feb;32(2):209-214. doi: 10.1111/jdv.14574. Epub 2017 Sep 14.
5
Melanosis of the lower lip subverted by filler injection: a simulator of early mucosal melanoma.填充剂注射导致的下唇黑变病：早期黏膜黑色素瘤的模拟病变
Australas J Dermatol. 2017 Feb;58(1):71-72. doi: 10.1111/ajd.12475.
6
Dermal fillers: pathophysiology, prevention and treatment of complications.真皮填充剂：病理生理学、并发症的预防与治疗
J Eur Acad Dermatol Venereol. 2017 Mar;31(3):405-413. doi: 10.1111/jdv.13977. Epub 2016 Oct 28.
7
Diagnosis of oral pigmentations and malignant transformations.口腔色素沉着及恶变的诊断。
Singapore Dent J. 2014 Dec;35C:39-46. doi: 10.1016/j.sdj.2014.03.001.
8
Complications of injectable fillers, part 2: vascular complications.注射用填充物的并发症，第 2 部分：血管并发症。
Aesthet Surg J. 2014 May 1;34(4):584-600. doi: 10.1177/1090820X14525035. Epub 2014 Apr 1.
9
Melanin: the biophysiology of oral melanocytes and physiological oral pigmentation.黑色素：口腔黑素细胞的生物生理学与生理性口腔色素沉着
Head Face Med. 2014 Mar 24;10:8. doi: 10.1186/1746-160X-10-8.
10
Delayed-onset complications of facial soft tissue augmentation with permanent fillers in 85 patients.85 例患者中永久性填充物行面部软组织填充后迟发性并发症。
Dermatol Surg. 2013 Oct;39(10):1474-85. doi: 10.1111/dsu.12313.