Franson J C, Murray H C, Bunck C
J Wildl Dis. 1985 Jan;21(1):33-9. doi: 10.7589/0090-3558-21.1.33.
Activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatine phosphokinase (CPK), and lactate dehydrogenase (LDH) were determined in plasma, kidney, liver, and muscle from five species of captive birds. Few differences occurred in plasma activities between sexes but considerable differences occurred between species. All five enzymes were detected in each of the tissues sampled. Relative enzyme activities in liver, kidney, and muscle were similar for each species. CPK activity was much higher in muscle than in liver or kidney and, of the five enzymes studied, may be the best indicator of muscle damage. Most of the other enzymes were more evenly distributed among the three tissues, and no organ-specific enzyme could be identified for liver or kidney. Because of interspecific variations in plasma enzyme activities, it is important to establish baseline values for each species to ensure accurate interpretation of results.
测定了五种圈养鸟类血浆、肾脏、肝脏和肌肉中丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、肌酸磷酸激酶(CPK)和乳酸脱氢酶(LDH)的活性。两性之间血浆活性差异不大,但不同物种之间差异显著。在所采集的每种组织中均检测到了这五种酶。每个物种肝脏、肾脏和肌肉中的相对酶活性相似。肌肉中的CPK活性远高于肝脏或肾脏,在所研究的五种酶中,它可能是肌肉损伤的最佳指标。其他大多数酶在这三种组织中分布更为均匀,无法确定肝脏或肾脏的器官特异性酶。由于血浆酶活性存在种间差异,为确保结果的准确解读,为每个物种建立基线值很重要。