Takeda I, Ohtsuki Y, Fujita K, Akagi T
Gan No Rinsho. 1985 Jan;31(1):102-6.
A case of poorly differentiated stromal tumor occurring in the left testis of a 37-year-old man is reported. Microscopically, the tumor was composed of polygonal cells arranged in a sheet-like pattern. The ill-defined cytoplasm contained disease-resistant PAS positive granules. Ultrastructurally, peculiar crystalloid structures were found in the cytoplasm of the tumor cells appearing in tubular, beaded or lamellar form and connected with the nuclear membrane as well as with the rough endoplasmic reticulum. These are somewhat similar to annulate lamellae. Interdigitation of the plasma membranes and zonula adherens was observed. Basal laminae were recognized in parts. These findings suggest that this tumor is a case of poorly differentiated gonadal stromal tumor showing a tendency to differentiate into Sertoli's cells.
报告了一例发生在一名37岁男性左侧睾丸的低分化间质瘤。显微镜下,肿瘤由呈片状排列的多边形细胞组成。界限不清的细胞质中含有抗淀粉酶PAS阳性颗粒。超微结构上,在肿瘤细胞的细胞质中发现了特殊的晶体结构,呈管状、串珠状或板层状,与核膜以及粗面内质网相连。这些结构与环状片层有些相似。观察到细胞膜的交错和黏着小带。部分区域可见基底膜。这些发现表明,该肿瘤是一例低分化性腺间质瘤,显示出向支持细胞分化的倾向。