Schöneberger Verena, Jonas Rahul A, Menghesha Leonie, Brockmann Claudia, Krohne Tim U, Cursiefen Claus, Fuchsluger Thomas A, Schaub Friederike
Department of Ophthalmology, University Medical Center Rostock, Rostock, Germany; and.
Department of Ophthalmology, Medical Faculty and University Hospital of Cologne, University of Cologne, Cologne, Germany.
Retina. 2025 Jun 1;45(6):1089-1096. doi: 10.1097/IAE.0000000000004408.
Formation of a full thickness macular hole (FTMH) after vitrectomy is rare. The aim of this study was to describe risk factors, clinical course, anatomical and functional prognosis of secondary FTMH development following surgery for primary rhegmatogenous retinal detachment.
This is a retrospective study. Eyes treated for rhegmatogenous retinal detachment at two centers between January 2012 and December 2022 were screened and those that developed secondary FTMH after pars plana vitrectomy without membrane peeling were included in our analysis.
Twenty-nine eyes (mean age 58.9 ± 9.5 years, 51.7% female) of 5,219 eyes developed secondary FTMH following pars plana vitrectomy for retinal detachment, equaling a rate of 0.56%. Median interval between vitrectomy and FTMH diagnosis was 14.0 months (Q1 2.0; Q3 61.0; range 1-373). Full thickness macular hole was treated by re-pars plana vitrectomy, Internal limiting membrane peeling, sulfur hexafluoride (SF6 20%-25%) endotamponade in 22, silicone oil in 6, and heavy silicone oil in one eye. In 88.0% FTMH, closure was observed after surgery. Postoperative mean visual acuity of all eyes was 20/145 Snellen (0.86 ± 0.76 logarithm of minimum angle of resolution) versus preoperative 20/215 (1.03 ± 0.43; P < 0.001).
Secondary FTMH after rhegmatogenous retinal detachment repair is a rare occurrence complication and can often be successfully treated by re-pars plana vitrectomy. Visual acuity improves following successful hole closure but less than that in primary FTMHs.
玻璃体切除术后形成全层黄斑裂孔(FTMH)较为罕见。本研究旨在描述原发性孔源性视网膜脱离手术后继发性FTMH发生的危险因素、临床过程、解剖和功能预后。
这是一项回顾性研究。对2012年1月至2022年12月期间在两个中心接受孔源性视网膜脱离治疗的眼睛进行筛查,纳入那些在玻璃体切除联合内界膜剥除术后发生继发性FTMH的患者进行分析。
在5219只接受视网膜脱离玻璃体切除术的眼睛中,有29只(平均年龄58.9±9.5岁,女性占51.7%)发生了继发性FTMH,发生率为0.56%。玻璃体切除术后至FTMH诊断的中位间隔时间为14.0个月(第一四分位数2.0;第三四分位数61.0;范围1 - 373)。22只眼睛通过再次玻璃体切除术、内界膜剥除、六氟化硫(SF6 20% - 25%)眼内填充治疗全层黄斑裂孔,6只眼睛使用硅油,1只眼睛使用重硅油。88.0%的FTMH在手术后观察到裂孔闭合。所有眼睛术后平均视力为Snellen 20/145(最小分辨角对数为0.86±0.76),术前为20/215(1.03±0.43;P < 0.001)。
孔源性视网膜脱离修复术后继发性FTMH是一种罕见的并发症,通常可通过再次玻璃体切除术成功治疗。裂孔成功闭合后视力有所改善,但不如原发性FTMH。