Alfred-Demas Roslyn, Daisley Hubert, Dalrymple Nicola, Alfred Renee, Thompson-Dillon Akilah
Internal Medicine, Tobago Regional Health Authority, Scarborough, TTO.
Pathology, Tobago Regional Health Authority, Scarborough, TTO.
Cureus. 2024 Dec 17;16(12):e75861. doi: 10.7759/cureus.75861. eCollection 2024 Dec.
Autoimmune hepatitis (AIH) is rare, and the diagnosis is not always clear-cut. It is associated with increased morbidity and mortality for the pregnant mother and fetus. Frequent pregnancy testing of women in childbearing years who have a known diagnosis of AIH may be necessary, even after counseling on family planning takes place. Close evaluation and a multidisciplinary approach are essential in pregnancy as disease sequelae can become progressive. We report an interesting case of hepatitis in pregnancy, with an eventful clinical history. The patient in hand was started on treatment with a positive response to steroids. The liver biopsy was not confirmatory, but the laboratory results and the clinical scenario pointed to autoimmune etiology. We wish to share relevant management lessons and highlight important caveats of learning for future clinical relevance, as well as the importance of a liver biopsy.
自身免疫性肝炎（AIH）较为罕见，诊断并不总是一目了然。它与妊娠母亲和胎儿的发病率及死亡率增加相关。对于已确诊AIH的育龄女性，即使在进行计划生育咨询后，也可能需要频繁进行妊娠检测。在妊娠期间，密切评估和多学科方法至关重要，因为疾病后遗症可能会进展。我们报告一例妊娠期间肝炎的有趣病例，其临床病史丰富。该患者开始接受治疗，对类固醇有阳性反应。肝活检结果不确诊，但实验室检查结果和临床情况指向自身免疫性病因。我们希望分享相关的管理经验教训，强调对未来临床相关性学习的重要注意事项，以及肝活检的重要性。
