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金银花在心血管疾病中的治疗潜力:一种抗炎干预策略。

The therapeutic potential of Honeysuckle in cardiovascular disease: an anti-inflammatory intervention strategy.

作者信息

Zhao Yue, Zhang Jiale, Lu Fei, Xu Weiming, Ma Qingxiao, Hu Jingqing

机构信息

Changchun University of Chinese Medicine Changchun, Jilin, China.

Institute of Basic Theory for Chinese Medicine, China Academy of Chinese Medical Sciences Beijing, China.

出版信息

Am J Transl Res. 2024 Dec 15;16(12):7262-7277. doi: 10.62347/NJMJ7853. eCollection 2024.

DOI:10.62347/NJMJ7853
PMID:39822489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11733370/
Abstract

Honeysuckle is a conventional Chinese medicine with several therapeutic applications. With the advancement of modern scientific technologies, Honeysuckle's pharmacological effects and medicinal properties have been investigated more thoroughly. Studies demonstrate that the bioactive compounds in Honeysuckle possess anti-inflammatory effects via several mechanisms, protecting the cardiovascular system. This article provides a reference for the clinical use of Honeysuckle by reviewing research on the therapeutic impact of Honeysuckle and its active constituents on cardiovascular diseases, such as coronary atherosclerotic heart disease (CHD), myocardial ischemia-reperfusion (MI/R), acute myocardial infarction (AMI), hypertension, arrhythmia, and heart failure, through the inhibition of inflammatory responses.

摘要

金银花是一种具有多种治疗用途的传统中药。随着现代科学技术的进步,金银花的药理作用和药用特性得到了更深入的研究。研究表明,金银花中的生物活性化合物通过多种机制具有抗炎作用,可保护心血管系统。本文通过综述金银花及其活性成分对心血管疾病如冠状动脉粥样硬化性心脏病(CHD)、心肌缺血再灌注(MI/R)、急性心肌梗死(AMI)、高血压、心律失常和心力衰竭的治疗作用的研究,为金银花的临床应用提供参考,其作用机制是通过抑制炎症反应来实现的。

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Arch Pharm (Weinheim). 2024 Oct;357(10):e2400240. doi: 10.1002/ardp.202400240. Epub 2024 Jul 15.
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