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翻修全髋关节置换术的趋势与流行病学:一项大型数据库研究

Trends and Epidemiology in Revision Total Hip Arthroplasty: A Large Database Study.

作者信息

Jones Conor M, Acuña Alexander J, Jan Kyleen, Forlenza Enrico M, Della Valle Craig J

机构信息

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.

出版信息

J Arthroplasty. 2025 Aug;40(8S1):S255-S261.e1. doi: 10.1016/j.arth.2025.01.011. Epub 2025 Jan 17.

Abstract

BACKGROUND

The clinical and financial burden of revision total hip arthroplasty (rTHA) continues to grow. Therefore, further investigation is needed to characterize case volume, reason for failure, and postoperative complications. The purpose of this study was to characterize contemporary indications for and complications following rTHA.

METHODS

Patients undergoing rTHA between 2010 and 2021 were identified within the PearlDiver database. Adjusted rTHA incidence was calculated by dividing the annual rTHA volume by the annual primary total hip arthroplasty (THA) and multiplying by 100,000. Mann-Kendall trend tests were utilized to trend revision volume, etiology, and 90-day postoperative complications. A total of 225,958 rTHAs were identified.

RESULTS

The annual volume of rTHA did not change over the study period (18,871 to 15,994; P = 0.064). However, the adjusted incidence of rTHA significantly decreased (20,169.3 to 13,061.2 per 100,000 THAs; P < 0.001). The most common causes of rTHA were aseptic implant loosening (21.5%), instability (19.8%), and infection (19.1%). The adjusted incidences of revision due to infection (4,659.9 to 2,596.1 per 100,000 THAs; P < 0.001) and aseptic implant loosening (4,651.4 to 2,493.2 per 100,000 THAs; P < 0.001) decreased over time. The adjusted rate of instability (3,149.8 to 3,245.3 per 100,000 THAs; P = 0.304) did not change. Rates of post-revision deep vein thrombosis, hematoma, surgical site infection, and transfusion significantly decreased over the study period (P < 0.05), while rates of emergency department visits and readmission did not change.

CONCLUSIONS

In addition to a decreased adjusted incidence of rTHA, our analysis demonstrated a decreased incidence of infection, aseptic loosening, and various postoperative complications. However, no difference in the adjusted incidence of instability and periprosthetic fracture was seen over our study period. Continued study is necessary to further decrease the need for rTHA with a focus on the etiologies and complications that have remained unchanged.

摘要

背景

翻修全髋关节置换术(rTHA)的临床和经济负担持续增加。因此,需要进一步研究以明确病例数量、失败原因及术后并发症。本研究的目的是明确rTHA的当代适应证及术后并发症。

方法

在PearlDiver数据库中识别出2010年至2021年间接受rTHA的患者。通过将每年rTHA的例数除以每年初次全髋关节置换术(THA)的例数,再乘以100,000来计算调整后的rTHA发病率。采用Mann-Kendall趋势检验来分析翻修例数、病因及术后90天并发症的变化趋势。共识别出225,958例rTHA。

结果

在研究期间,rTHA的年度例数未发生变化(从18,871例降至15,994例;P = 0.064)。然而,rTHA的调整发病率显著下降(从每100,000例THA中20,169.3例降至13,061.2例;P < 0.001)。rTHA最常见的原因是无菌性植入物松动(21.5%)、不稳定(19.8%)和感染(19.1%)。因感染导致的翻修调整发病率(从每100,000例THA中4,659.9例降至2,596.1例;P < 0.001)和无菌性植入物松动导致的翻修调整发病率(从每100,000例THA中4,651.4例降至2,493.2例;P < 0.001)随时间下降。不稳定的调整发病率(从每100,000例THA中3,149.8例升至3,245.3例;P = 0.304)未发生变化。在研究期间,翻修后深静脉血栓形成、血肿、手术部位感染及输血的发生率显著下降(P < 0.05),而急诊就诊率和再入院率未发生变化。

结论

除了rTHA的调整发病率下降外,我们的分析还表明感染、无菌性松动及各种术后并发症的发生率降低。然而,在我们的研究期间,不稳定和假体周围骨折的调整发病率没有差异。有必要继续开展研究,以进一步减少rTHA的需求,重点关注那些未发生变化的病因和并发症。

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