Suppr超能文献

一项关于从磺脲类药物或胰岛素转换为新型糖尿病药物的全国医生调查。

A National Physician Survey Examining Switching From Sulfonylureas or Insulin to Newer Diabetes Medications.

作者信息

Pilla Scott J, Wang Isabelle J, Tang Olive, Schoenborn Nancy L, Boyd Cynthia M, Bancks Michael P, Mathioudakis Nestoras N, Maruthur Nisa M

机构信息

Department of Medicine, Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD.

出版信息

Clin Diabetes. 2024 Sep 5;43(1):33-42. doi: 10.2337/cd24-0043. eCollection 2025 Winter.

Abstract

This study was a national survey of U.S. physicians in general medicine, geriatrics, or endocrinology who were asked what medication change they would make for adults with type 2 diabetes taking sulfonylureas or insulin with an A1C below their individualized goal. Responding physicians switched the hypoglycemia-causing medication a median of 4 times (interquartile range 1-9) among 27 opportunities and selected dipeptidyl peptidase 4 inhibitors most often when switching. Sodium-glucose cotransporter 2 inhibitors were selected less frequently, including when indicated for cardiovascular and renal comorbidities, but significantly more often among physicians caring for a greater proportion of patients with private health insurance. Overcoming barriers to switching hypoglycemia-causing medications may help to reduce rates of hypoglycemia while targeting cardiovascular and renal comorbidities.

摘要

这项研究是一项针对美国普通内科、老年医学或内分泌学领域医生的全国性调查,这些医生被问及对于糖化血红蛋白(A1C)低于个体化目标值的服用磺脲类药物或胰岛素的2型糖尿病成人患者,他们会做出何种药物调整。做出回应的医生在27次机会中,将导致低血糖的药物更换了中位数为4次(四分位间距为1 - 9),更换时最常选择二肽基肽酶4抑制剂。钠-葡萄糖协同转运蛋白2抑制剂的选择频率较低,包括在有心血管和肾脏合并症指征时,但在照顾有私人医疗保险的患者比例更高的医生中选择频率显著更高。克服更换导致低血糖药物的障碍可能有助于降低低血糖发生率,同时针对心血管和肾脏合并症。

相似文献

本文引用的文献

4
13. Older Adults: Standards of Care in Diabetes-2024.13. 老年人:2024年糖尿病护理标准
Diabetes Care. 2024 Jan 1;47(Suppl 1):S244-S257. doi: 10.2337/dc24-S013.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验