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Estimating myocardial fibrosis in aortic stenosis using the serum collagen type I C-terminal telopeptide to matrix metalloproteinase-1 ratio.

作者信息

Gersch Svante, Bengel Philipp, Paul Niels B, Ravassa Susana, von Haehling Stephan, Fischer Andreas, Zeisberg Elisabeth M, Puls Miriam, Hasenfuß Gerd, Schnelle Moritz

机构信息

Department of Clinical Chemistry Department of Cardiology and Pneumology University Medical Center Göttingen Göttingen Germany.

Program of Cardiovascular Disease Centro de Investigacion Medica Aplicada Universidad de Navarra (CIMA) Pamplona Spain.

出版信息

MedComm (2020). 2025 Jan 16;6(2):e70069. doi: 10.1002/mco2.70069. eCollection 2025 Feb.

DOI:10.1002/mco2.70069
PMID:39830018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11739461/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de4d/11739461/4e591fe5c63b/MCO2-6-e70069-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de4d/11739461/4e591fe5c63b/MCO2-6-e70069-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de4d/11739461/4e591fe5c63b/MCO2-6-e70069-g001.jpg

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本文引用的文献

1
Biomarker-based assessment of collagen cross-linking identifies patients at risk of heart failure more likely to benefit from spironolactone effects on left atrial remodelling. Insights from the HOMAGE clinical trial.基于生物标志物的胶原交联评估可识别出更有可能从螺内酯对左心房重构的影响中获益的心力衰竭风险患者。来自 HOMAGE 临床试验的见解。
Eur J Heart Fail. 2022 Feb;24(2):321-331. doi: 10.1002/ejhf.2394. Epub 2021 Dec 9.
2
Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis.在严重主动脉瓣狭窄的不同血流动力学亚型中,心肌纤维化对经导管主动脉瓣植入术后左心室重构、恢复及预后的影响。
Eur Heart J. 2020 May 21;41(20):1903-1914. doi: 10.1093/eurheartj/ehaa033.
3
Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial.基于生物标志物的心肌纤维化表型分析鉴定出射血分数保留的心力衰竭患者对螺内酯有益作用的抵抗:来自 Aldo-DHF 试验的结果。
Eur J Heart Fail. 2018 Sep;20(9):1290-1299. doi: 10.1002/ejhf.1194. Epub 2018 Apr 30.
4
Myocardial Collagen Cross-Linking Is Associated With Heart Failure Hospitalization in Patients With Hypertensive Heart Failure.心肌胶原交联与高血压性心力衰竭患者心力衰竭住院相关。
J Am Coll Cardiol. 2016 Jan 26;67(3):251-60. doi: 10.1016/j.jacc.2015.10.063.
5
Circulating Biomarkers of Myocardial Fibrosis: The Need for a Reappraisal.循环心肌纤维化生物标志物:重新评估的必要性。
J Am Coll Cardiol. 2015 Jun 9;65(22):2449-56. doi: 10.1016/j.jacc.2015.04.026.