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静脉注射脂质乳剂用于治疗一名三个月大患者的局部麻醉药中毒

Intravenous Lipid Emulsion for Managing Local Anesthetic Toxicity in a Three-Month-Old Patient.

作者信息

Alquzi Abdulrahman S, Alsabban Bader, Bokhari Ahmed

机构信息

Anesthesia Department, King Abdulaziz Medical City, Jeddah, SAU.

出版信息

Cureus. 2024 Dec 18;16(12):e75981. doi: 10.7759/cureus.75981. eCollection 2024 Dec.

Abstract

Local anesthetic systemic toxicity (LAST) is a well-known life-threatening local anesthetics complication, especially if given in inappropriate doses or routes. Therefore, physicians should be aware of LAST symptoms, such as neurological and cardiac symptoms. In addition, they should always consider it in the differential diagnosis when they encounter similar symptoms. The early recognition of LAST and initiation of intravenous lipid emulsion (ILE) can decrease mortality and morbidity rates. Multiple organizations and guidelines use ILE as standard LAST management. We present a three-month-old infant who received a caudal block that was complicated by an inadvertent intravascular injection that led to LAST cardiac symptoms. ILE successfully managed these symptoms, and the patient returned to normal vital signs without any complications.

摘要

局部麻醉药全身毒性反应(LAST)是一种众所周知的危及生命的局部麻醉药并发症,尤其是在剂量不当或给药途径不当时。因此,医生应了解LAST的症状,如神经和心脏症状。此外,当他们遇到类似症状时,应始终将其纳入鉴别诊断。早期识别LAST并开始静脉输注脂质乳剂(ILE)可降低死亡率和发病率。多个组织和指南将ILE用作标准的LAST治疗方法。我们报告一名三个月大的婴儿,其接受了骶管阻滞,因意外血管内注射而出现LAST心脏症状。ILE成功地控制了这些症状,患者生命体征恢复正常,未出现任何并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2456/11742267/959463ff2a6a/cureus-0016-00000075981-i01.jpg

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