Randolino Juan Pablo, González Emanuel, Laura Gaitán, Gastón Slullitel, Alvarez Gonzalo, Maximiliano Seletti, López Valeria
Instituto de Ortopedia y Trauma Dr. Jaime Slullitel, San LUIS 2534 2000, Rosario, Santa Fe, Argentina.
Hospital Escuela Eva Perón, Av. San Martin 1645, Granadero Baigorria, Santa Fe, Argentina.
J Clin Orthop Trauma. 2024 Dec 7;61:102848. doi: 10.1016/j.jcot.2024.102848. eCollection 2025 Feb.
In the scenario of chronic osteomyelitis following an ankle fracture, limb salvage and ideally infection eradication, can be an alternative to amputation.Tibiotalocalcaneal arthrodesis is perhaps the most popular procedure. When performing fusion in osteomyelitis patients, external fixation is more commonly used, although there is some experience with internal fixation. In this study, we conducted a retrospective evaluation of three groups of consecutively treated patients undergoing tibiotalocalcaneal fusion using either circular or monoplanar external fixation or an intramedullary nail coated with antibiotic-loaded cement. Our objective was to assess the success of each procedure in terms of consolidation, infection remission, and improvement in the quality of life.
A multicenter, retrospective, study of 17 patients treated with tibiotalocalcaneal fusion, divided into three groups based on the treatment performed: Group A: retrograde intramedullary nail coated with Polymethylmethacrylate (PMMA) with antibiotic, Group B: monoplanar LRS (Limb Reconstruction System) external fixator, and Group C: circular external fixator; all with a minimum 12 month follow-up. Quality and percentage of consolidation were evaluated through tomography. Additionally, the SF-12 form was administered to assess the quality of life at the last follow-up visit.
17 patients were evaluated. Group A: 6 patients, average tibiotalar and subtalar consolidation rates were 66.24 % and 67.06 %. One patient did not achieve infection healing. SF-12 scores averaged 40 for physical and 48.13 for mental. Group B: 5 patients; 3 active smokers. Average tibiotalar and subtalar consolidation rates were 52.78 % and 62.3 %, respectively. All patients achieved infection remission. SF-12 scores averaged 46.7 for physical and 51.3 for mental. Group C:6 patients, 1 diabetic and 3 smokers. Average tibiotalar and subtalar consolidation rates were 65.9 % and 65.7 %. Half experienced infection recurrence. SF-12 scores averaged 36.7 for physical and 47.8 for mental.
Patients with coated retrograde nails exhibit higher consolidation rates; and patients with circular external fixation had a higher infection recurrence rate. Establishing generalizable treatment algorithms for these patients remains challenging, but our data suggest a favorable trend toward the use of internal intramedullary fixation coated with PMMA.
在踝关节骨折后慢性骨髓炎的情况下,保肢并理想地根除感染可作为截肢的替代方案。胫距跟关节融合术可能是最常用的手术。在骨髓炎患者中进行融合时,更常使用外固定,尽管也有一些内固定的经验。在本研究中,我们对三组连续接受胫距跟融合术的患者进行了回顾性评估,这些患者分别使用环形或单平面外固定或涂有载抗生素骨水泥的髓内钉。我们的目的是从骨愈合、感染缓解和生活质量改善方面评估每种手术的成功率。
一项多中心回顾性研究,对接受胫距跟融合术的17例患者进行研究,根据所进行的治疗分为三组:A组:涂有含抗生素聚甲基丙烯酸甲酯(PMMA)的逆行髓内钉;B组:单平面肢体重建系统(LRS)外固定器;C组:环形外固定器;所有患者均进行了至少12个月的随访。通过断层扫描评估骨愈合的质量和百分比。此外,在最后一次随访时使用SF - 12量表评估生活质量。
评估了17例患者。A组:6例患者,胫距关节和距下关节的平均骨愈合率分别为66.24%和67.06%。1例患者感染未愈合。SF - 12身体评分平均为40分,精神评分为48.13分。B组:5例患者;3例为现吸烟者。胫距关节和距下关节的平均骨愈合率分别为52.78%和62.3%。所有患者感染均缓解。SF - 12身体评分平均为46.7分,精神评分为51.3分。C组:6例患者,1例糖尿病患者,3例吸烟者。胫距关节和距下关节的平均骨愈合率分别为65.9%和65.7%。半数患者感染复发。SF - 12身体评分平均为36.7分,精神评分为47.8分。
涂有涂层的逆行髓内钉治疗的患者骨愈合率较高;环形外固定治疗的患者感染复发率较高。为这些患者建立通用的治疗方案仍然具有挑战性,但我们的数据表明使用涂有PMMA的髓内固定有良好的趋势。