Matthay Ellicott C, Gobaud Ariana N, Branas Charles C, Keyes Katherine M, Roy Brita, Cerdá Magdalena
Center for Opioid Epidemiology and Policy, Division of Epidemiology, Department of Population Health, New York University Grossman School of Medicine, New York, New York.
Department of Epidemiology, Columbia Mailman School of Public Health, New York, New York.
Alcohol Res. 2025 Jan 10;45(1):01. doi: 10.35946/arcr.v45.1.01. eCollection 2025.
Firearm violence remains a leading cause of death and injury in the United States. Prior research supports that alcohol exposures, including individual-level alcohol use and alcohol control policies, are modifiable risk factors for firearm violence, yet additional research is needed to support prevention efforts.
This scoping review aims to update a prior 2016 systematic review on the links between alcohol exposure and firearm violence to examine whether current studies indicate causal links between alcohol use, alcohol interventions, and firearm violence-related outcomes.
Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines, a comprehensive search of published studies was conducted, replicating the search strategy of the prior review but focusing on studies published since 2015. The review included published studies of humans, conducted in general populations of any age, gender, or racial/ethnic group, that examined the relationship between an alcohol-related exposure and an outcome involving firearm violence or risks for firearm violence. Excluded were small studies restricted to special populations, forensic or other technical studies, non-original research articles such as reviews, and studies that relied solely on descriptive statistics or did not adjust for confounders.
The review included published studies indexed in PubMed, Web of Science, and Scopus. Eligible articles were published on or after January 1, 2015. The latest search was conducted on December 15, 2023.
Using a structured data collection instrument, data were extracted on the characteristics of each study, including the dimension of alcohol exposure, the dimension of firearm violence, study population, study design, statistical analysis, source of funding, main findings, and whether effect measure modification was assessed and, if so, along what dimensions. Two authors independently conducted title/abstract screening, full-text screening, and data extraction until achieving 95% agreement, with discrepancies resolved through discussion.
The search yielded 797 studies. Of these, 754 were excluded and 43 met the final inclusion criteria. Studies addressed a range of alcohol exposures and firearm violence-related outcomes, primarily with cross-sectional study designs; 40% considered effect measure modification by any population characteristic. Findings from the 21 studies examining the relationship of individual-level alcohol use or alcohol use disorder (AUD) with firearm ownership, access, unsafe storage, or carrying indicated a strong and consistent positive association. Seven studies examined associations of individual-level alcohol use or AUD with firearm injury or death; these also indicated a pattern of positive associations, but the magnitude and precision of the estimates varied. Eight studies examined the impact of neighborhood proximity or density of alcohol outlets and found mixed results that were context- and study design-dependent. Two studies linked prior alcohol-related offenses to increased risk of firearm suicide and perpetration of violent firearm crimes among a large cohort of people who purchased handguns, and two studies linked policies prohibiting firearm access among individuals with a history of alcohol-related offenses to reductions in firearm homicide and suicide. Finally, four studies examined alcohol control policies and found that greater restrictiveness was generally associated with reductions in firearm homicide or firearm suicide.
Findings from this scoping review continue to support a causal relationship between alcohol exposures and firearm violence that extends beyond acute alcohol use to include AUD and alcohol-related policies. Policies controlling the availability of alcohol and prohibiting firearm access among individuals with alcohol-related offense histories show promise for the prevention of firearm violence. Additional research examining differential impacts by population subgroup, alcohol use among perpetrators of firearm violence, policies restricting alcohol outlet density, and randomized or quasi-experimental study designs with longitudinal follow-up would further support inferences to inform prevention efforts.
枪支暴力仍然是美国死亡和受伤的主要原因。先前的研究表明,酒精暴露,包括个人层面的饮酒行为和酒精控制政策,是枪支暴力的可改变风险因素,但仍需要更多研究来支持预防工作。
本范围综述旨在更新2016年关于酒精暴露与枪支暴力之间联系的系统综述,以研究当前研究是否表明饮酒、酒精干预与枪支暴力相关结果之间存在因果关系。
按照系统综述和Meta分析扩展的范围综述首选报告项目(PRISMA-ScR)指南,对已发表的研究进行了全面检索,重复了先前综述的检索策略,但重点关注2015年以来发表的研究。该综述纳入了针对任何年龄、性别或种族/族裔群体的一般人群进行的已发表的人体研究,这些研究考察了与酒精相关的暴露与涉及枪支暴力或枪支暴力风险的结果之间的关系。排除的研究包括限于特殊人群的小型研究、法医或其他技术研究、非原创研究文章(如综述),以及仅依赖描述性统计或未对混杂因素进行调整的研究。
该综述纳入了在PubMed、科学网和Scopus中索引的已发表研究。符合条件的文章于2015年1月1日或之后发表。最近一次检索于2023年12月15日进行。
使用结构化数据收集工具,提取了每项研究的特征数据,包括酒精暴露维度、枪支暴力维度、研究人群、研究设计、统计分析、资金来源、主要发现,以及是否评估了效应测量修正(若评估了,则包括在哪些维度上进行评估)。两位作者独立进行标题/摘要筛选、全文筛选和数据提取,直至达成95%的一致意见,如有分歧则通过讨论解决。
检索共获得797项研究。其中,754项被排除,43项符合最终纳入标准。这些研究涉及一系列酒精暴露和枪支暴力相关结果,主要采用横断面研究设计;40%的研究考虑了任何人群特征对效应测量的修正。21项研究考察了个人层面的饮酒行为或酒精使用障碍(AUD)与枪支拥有、获取、不安全储存或携带之间的关系,结果表明存在强烈且一致的正相关。7项研究考察了个人层面的饮酒行为或AUD与枪支伤害或死亡之间的关联;这些研究也显示出正相关的模式,但估计值的大小和精度有所不同。8项研究考察了邻里附近或酒精销售点密度的影响,结果不一,取决于具体情境和研究设计。两项研究将先前与酒精相关的犯罪与一大群购买手枪的人自杀和实施暴力枪支犯罪的风险增加联系起来,两项研究将禁止有酒精相关犯罪史的个人获取枪支的政策与枪支杀人及自杀率的降低联系起来。最后,4项研究考察了酒精控制政策,发现更高的限制性通常与枪支杀人或枪支自杀率的降低相关。
本范围综述的结果继续支持酒精暴露与枪支暴力之间的因果关系,这种关系不仅限于急性饮酒,还包括AUD和与酒精相关的政策。控制酒精供应以及禁止有酒精相关犯罪史的个人获取枪支的政策在预防枪支暴力方面显示出前景。进一步研究不同人群亚组的差异影响、枪支暴力实施者的饮酒情况、限制酒精销售点密度的政策,以及采用纵向随访的随机或准实验研究设计,将进一步支持为预防工作提供信息的推断。