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巨大的、重达十六磅的颈部多形性腺瘤恶变癌

Gigantic, Sixteen-Pound Carcinoma Ex Pleomorphic Adenoma of the Neck.

作者信息

Rothka Andrew J, Ferraro Maria, Bavier Richard, Saltagi Mohamad, Bhele Sanica, Goyal Neerav, Slonimsky Guy

机构信息

Penn State College of Medicine Hershey Pennsylvania USA.

Saint Francis University Loretto Pennsylvania USA.

出版信息

Clin Case Rep. 2025 Jan 16;13(1):e70048. doi: 10.1002/ccr3.70048. eCollection 2025 Jan.

DOI:10.1002/ccr3.70048
PMID:39831137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11738647/
Abstract

Carcinoma ex pleomorphic adenomas are rare malignant tumors of the salivary glands, primarily seen in older adults. They originate from benign pleomorphic adenomas, are aggressive, and have poorer prognosis. This case documents an unusual presentation of a massive carcinoma ex pleomorphic adenoma.

摘要

多形性腺瘤癌变是一种罕见的涎腺恶性肿瘤，主要见于老年人。它起源于良性多形性腺瘤，具有侵袭性，预后较差。本病例记录了一例巨大多形性腺瘤癌变的不寻常表现。

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本文引用的文献

1
TERT Promoter Mutation in Benign and Malignant Salivary Gland Tumors; A Cross-Sectional Study.良性和恶性涎腺肿瘤中的端粒酶逆转录酶启动子突变；一项横断面研究。
Iran J Pathol. 2023;18(1):64-74. doi: 10.30699/IJP.ijp.2023.556651.2927. Epub 2023 Mar 23.
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Systematic review of prognostic factors in carcinoma ex pleomorphic adenoma.癌在多形性腺瘤中预后因素的系统评价。
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Carcinoma ex pleomorphic adenoma of the parotid gland.腮腺多形性腺瘤癌变。
Am J Otolaryngol. 2022 Mar-Apr;43(2):103389. doi: 10.1016/j.amjoto.2022.103389. Epub 2022 Feb 3.
4
Carcinoma ex pleomorphic adenoma of major salivary glands: CT and MR imaging findings.涎腺多形性腺瘤癌变：CT 和 MRI 影像学表现。
Dentomaxillofac Radiol. 2021 Oct 1;50(7):20200485. doi: 10.1259/dmfr.20200485. Epub 2021 Jun 23.
5
Surgery combined with I brachytherapy for treatment of carcinoma ex pleomorphic adenoma of the parotid gland.手术联合近距离放疗治疗腮腺多形性腺瘤癌变。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Apr;131(4):395-404. doi: 10.1016/j.oooo.2020.11.017. Epub 2020 Dec 8.
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Carcinoma Ex-Pleomorphic Adenoma Diagnosis During Global Health Engagement Operations.全球健康参与行动期间的癌型多形性腺瘤的诊断。
Mil Med. 2021 Jan 25;186(Suppl 1):828-832. doi: 10.1093/milmed/usaa448.
7
Risk factors for carcinoma ex pleomorphic adenoma in patients presenting with recurrence after resection of pleomorphic adenoma.复发性多形性腺瘤切除术后复发患者的癌在多形性腺瘤中风险因素。
Head Neck. 2021 Feb;43(2):419-427. doi: 10.1002/hed.26489. Epub 2020 Oct 12.
8
Promoter region mutations of the telomerase reverse transcriptase (TERT) gene in head and neck squamous cell carcinoma.端粒酶逆转录酶（TERT）基因启动子区突变与头颈部鳞状细胞癌。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul;130(1):63-70. doi: 10.1016/j.oooo.2020.02.015. Epub 2020 May 11.
9
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Am J Otolaryngol. 2019 Nov-Dec;40(6):102279. doi: 10.1016/j.amjoto.2019.102279. Epub 2019 Aug 21.
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Ear Nose Throat J. 2019 Sep;98(8):504-509. doi: 10.1177/0145561319855376. Epub 2019 Jun 13.