Fadel Leandro, Rabelo Rodrigo Cardoso, Fantoni Denise Tabacchi, Machado Gustavo, Duarte Marina Candido, Schaefer Gabriela da Cruz, Oliveira Mariana Pires, Fadel Jessica de Oliveira Lara Castanheira, Morais Kamila Dos Santos, Pereira-Neto Glaucia Bueno, da Costa Fernanda Vieira Amorim
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, Oklahoma, USA.
Intensivet, Brasília, Brazil.
J Vet Emerg Crit Care (San Antonio). 2025 Jan-Feb;35(1):34-40. doi: 10.1111/vec.13446. Epub 2025 Jan 20.
To prospectively compare the shock index (SI) in a population of healthy cats with a population of cats presenting to the emergency room (ER) deemed to be in a state of shock.
Prospective cohort study of cats.
University teaching hospital.
Twenty-seven healthy control cats were enrolled to establish a reference interval, and 27 cats were enrolled that were presented to the ER with clinical signs of shock. Shock was defined as abnormalities in at least 2 of the following inclusion criteria: plasma lactate concentration > 2.5 mmol/L; peripheral vasoconstriction (at least 2 of the following parameters: capillary refill time >3 s, rectal-interdigital temperature gradient [RITG] >8°C, femoral pulse not palpable, pale mucous membranes); or systolic blood pressure (SBP) < 100 mm Hg.
Upon presentation, SI (SI = heart rate [HR]/SBP), HR, SBP, and RITG were recorded in both groups, along with peripheral venous blood sampling for lactate measurement.
The mean SI in the control group was 1.47 ± 0.2 and was 1.87 ± 0.47 in the shock group (P = 0.001). Using equality in sensitivity and specificity of 0.7, an SI cutoff point of 1.54 (95% confidence interval [CI]: 0.49-0.86) was determined with an estimated area under the receiver operating characteristic curve of 0.78 (95% CI: 0.65-0.90). HR, plasma lactate concentration, and RITG did not differ between the groups. Systolic arterial blood pressure (P = 0.01), rectal temperature (P = 0.02), and interdigital temperature (P = 0.04) differed significantly.
The SI is a noninvasive, easy, and reliable parameter for distinguishing cats in shock from normal cats.
前瞻性比较健康猫群体与送至急诊室（ER）且被认为处于休克状态的猫群体的休克指数（SI）。
猫的前瞻性队列研究。
大学教学医院。
纳入27只健康对照猫以建立参考区间，纳入27只出现休克临床症状并送至ER的猫。休克定义为至少符合以下2项纳入标准异常：血浆乳酸浓度>2.5 mmol/L；外周血管收缩（以下参数中至少2项：毛细血管再充盈时间>3秒、直肠-趾间温度梯度[RITG]>8°C、股动脉搏动未触及、黏膜苍白）；或收缩压（SBP）<100 mmHg。
两组猫就诊时均记录SI（SI =心率[HR]/SBP）、HR、SBP和RITG，并采集外周静脉血样进行乳酸测量。
对照组平均SI为1.47±0.2，休克组为1.87±0.47（P = 0.001）。采用灵敏度和特异度均为0.7，确定SI临界值为1.54（95%置信区间[CI]：0.49 - 0.86），估计受试者工作特征曲线下面积为0.78（95% CI：0.65 - 0.90）。两组间HR、血浆乳酸浓度和RITG无差异。收缩动脉血压（P = 0.01）、直肠温度（P = 0.02）和趾间温度（P = 0.04）差异显著。
SI是区分休克猫与正常猫的一种无创、简便且可靠的参数。
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