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Positive margins after breast-conserving surgery: is it possible to hang up the scalpel in the era of precision medicine?

作者信息

Franceschini Gianluca, D'Archi Sabatino, Di Leone Alba, Masetti Riccardo

机构信息

Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8, 00168, Rome, Italy.

出版信息

Updates Surg. 2025 Apr;77(2):265-266. doi: 10.1007/s13304-025-02067-7. Epub 2025 Jan 20.

DOI:10.1007/s13304-025-02067-7
PMID:39831929
Abstract
摘要

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Positive margins after breast-conserving surgery: is it possible to hang up the scalpel in the era of precision medicine?保乳手术后切缘阳性：在精准医学时代是否有可能放下手术刀？
Updates Surg. 2025 Apr;77(2):265-266. doi: 10.1007/s13304-025-02067-7. Epub 2025 Jan 20.
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MRI predictors of tumor-positive margins after breast-conserving surgery.保乳手术后肿瘤阳性切缘的 MRI 预测因子。
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[Preoperative dynamic contrast-enhanced MRI can reduce the rate of tumor-positive resection margins after breast conserving surgery in patients with early non-mass breast carcinoma].[术前动态对比增强磁共振成像可降低早期非肿块型乳腺癌患者保乳手术后肿瘤阳性切缘率]
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Preoperative breast MRI can reduce the rate of tumor-positive resection margins and reoperations in patients undergoing breast-conserving surgery.术前乳腺 MRI 可降低保乳手术患者肿瘤阳性切缘和再次手术的发生率。
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Technologies and techniques to improve precision in breast conserving surgery.提高保乳手术精准度的技术与技巧。
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引用本文的文献

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Re-Excision After Positive Margins in Breast-Conserving Surgery: Can a Risk-Based Strategy Avoid Unnecessary Surgery?保乳手术切缘阳性后的再次切除：基于风险的策略能否避免不必要的手术？
J Clin Med. 2025 Aug 18;14(16):5839. doi: 10.3390/jcm14165839.

本文引用的文献

1
Efficacy of radiation therapy in Japanese patients with positive margins after breast-conserving surgery.保乳手术后切缘阳性的日本患者放射治疗的疗效。
Jpn J Clin Oncol. 2024 May 7;54(5):556-561. doi: 10.1093/jjco/hyad196.
2
EUSOMA quality indicators for non-metastatic breast cancer: An update.EUSOMA 非转移性乳腺癌质量指标：更新版。
Eur J Cancer. 2024 Feb;198:113500. doi: 10.1016/j.ejca.2023.113500. Epub 2023 Dec 26.
3
Performance of standardized tasks and evidence-based surgery may increase the chance of success in breast conserving treatment.
标准化任务的执行和循证手术可能会增加保乳治疗成功的机会。
Gland Surg. 2020 Aug;9(4):1069-1071. doi: 10.21037/gs-20-523.
4
Involved margins after lumpectomy for breast cancer: Always to be re-excised?乳腺癌保乳术后切缘阳性：是否都需要再次切除？
Surg Oncol. 2019 Sep;30:141-146. doi: 10.1016/j.suronc.2019.08.002. Epub 2019 Aug 6.
5
Omitting re-excision for focally positive margins after breast-conserving surgery does not impair disease-free and overall survival.保乳手术后对于切缘局部阳性不进行再次切除不会损害无病生存率和总生存率。
Breast Cancer Res Treat. 2017 Jul;164(1):157-167. doi: 10.1007/s10549-017-4232-6. Epub 2017 Apr 7.