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腹腔镜机器人辅助下克罗恩病患儿回盲部切除术并体内吻合术:一家儿科中心的初步经验及手术可行性

Laparoscopic robotic-assisted ileo-caecal resection with intracorporeal anastomosis in children with Crohn disease: initial experience of a paediatric center and surgical feasibility.

作者信息

Wong Michela Cing Yu, Rotondi Giulia, Avanzini Stefano, Arrigo Serena, Mattioli Girolamo

机构信息

Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, Largo Gaslini 5, 16147, Genoa, Italy.

DINOGMI, University of Genoa, Genoa, Italy.

出版信息

Pediatr Surg Int. 2025 Jan 17;41(1):68. doi: 10.1007/s00383-024-05961-0.

DOI:10.1007/s00383-024-05961-0
PMID:39831981
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11753335/
Abstract

PURPOSE

Pediatric-onset Crohn's disease (CD) presents with a more aggressive course than adults. Surgical treatment is still necessary in many patients. The laparoscopic technique for treating terminal ileal CD is deemed safe and feasible, with the advantage to perform an intra-corporeal anastomosis (ICA). The robotic platform facilitates ICA creation thanks to 3D-visualization, tenfold magnification and better dexterity. The aim of this study was to report our initial experience of robotic ileocecal resection (RICR) with ICA in children with CD.

METHODS

Six patients underwent RICR for CD. Patient characteristics, intraoperative details, and postoperative outcomes were collected. The surgical technique consisted in an intra-corporeal ICR with a stapled side-to-side ileo-colic anastomosis.

RESULTS

The mean age at surgery was 14.8 years. The mean operative time was 210.8 min. No intraoperative complications or conversions were recorded. Bowel function returned on postoperative day 3 and the mean hospital stay was 8 days. Two minor complications were treated conservatively and 1 major (anastomotic dehiscence) required reoperation.

CONCLUSION

RICR is a safe and feasible technique in pediatric CD of terminal ileum. The robot offers advantages over other techniques for the precision of the suture, avoiding extracorporeal anastomosis. However, larger studies are needed to confirm these preliminary results.

摘要

目的

儿童期发病的克罗恩病(CD)的病程比成人更具侵袭性。许多患者仍需要手术治疗。腹腔镜技术治疗末端回肠克罗恩病被认为是安全可行的,其优点是能够进行体内吻合术(ICA)。机器人平台借助三维可视化、十倍放大率和更好的灵活性,便于进行体内吻合术。本研究的目的是报告我们在患有克罗恩病的儿童中进行机器人辅助回盲部切除术(RICR)并进行体内吻合术的初步经验。

方法

6例患者接受了用于治疗克罗恩病的机器人辅助回盲部切除术。收集了患者的特征、术中细节和术后结果。手术技术包括进行体内回盲部切除并采用吻合器进行侧侧回结肠吻合术。

结果

手术时的平均年龄为14.8岁。平均手术时间为210.8分钟。未记录到术中并发症或中转开腹情况。术后第3天肠道功能恢复,平均住院时间为8天。2例轻微并发症采用保守治疗,1例严重并发症(吻合口裂开)需要再次手术。

结论

机器人辅助回盲部切除术在儿童末端回肠克罗恩病中是一种安全可行的技术。与其他技术相比,机器人在缝合精度方面具有优势,避免了体外吻合。然而,需要更大规模的研究来证实这些初步结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/af1e72306d92/383_2024_5961_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/1efd6a329cc0/383_2024_5961_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/b57eeaf08580/383_2024_5961_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/88f08357e9f1/383_2024_5961_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/20b6393a4557/383_2024_5961_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/af1e72306d92/383_2024_5961_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/1efd6a329cc0/383_2024_5961_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/6a7226f03ed7/383_2024_5961_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/b57eeaf08580/383_2024_5961_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/88f08357e9f1/383_2024_5961_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/20b6393a4557/383_2024_5961_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/737d/11753335/af1e72306d92/383_2024_5961_Fig6_HTML.jpg

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本文引用的文献

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ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment.ECCO 指南:克罗恩病治疗——手术治疗。
J Crohns Colitis. 2024 Oct 15;18(10):1556-1582. doi: 10.1093/ecco-jcc/jjae089.
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Cost analysis of new robotic competitors: a comparison of direct costs for initial hospital stay between Da Vinci and Hugo RAS for radical prostatectomy.新型机器人竞争者的成本分析:达芬奇与 Hugo RAS 根治性前列腺切除术初始住院费用的直接成本比较。
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Minimally Invasive Surgery for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Robotic Versus Laparoscopic Surgical Techniques.
微创外科治疗炎症性肠病:机器人与腹腔镜手术技术的系统评价和荟萃分析。
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Ileocolic resection for Crohn's disease: robotic intracorporeal compared to laparoscopic extracorporeal anastomosis.克罗恩病的回肠结肠切除术:机器人经体内与腹腔镜经体外吻合的比较。
J Robot Surg. 2023 Oct;17(5):2157-2166. doi: 10.1007/s11701-023-01635-6. Epub 2023 Jun 1.
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Complications and Disease Recurrence After Ileocecal Resection in Pediatric Crohn's Disease: A Retrospective Study.小儿克罗恩病回肠末端切除术后的并发症和疾病复发:一项回顾性研究。
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Comparison of laparoscopic and open ileocecal resection for Crohn's disease in children.腹腔镜与开腹回肠结肠切除术治疗儿童克罗恩病的比较。
Pediatr Surg Int. 2023 Feb 27;39(1):140. doi: 10.1007/s00383-023-05419-9.
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Robotic Surgery in Crohn's Disease.克罗恩病的机器人手术
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