超声支气管镜引导下碘-125粒子植入治疗淋巴结转移瘤的新疗法：1例报告。 （备注：你提供的英文原文中“MCAO”表述有误，根据语境推测应该是“lymph node metastasis”即淋巴结转移，按照正确内容翻译。）
EBUS-guided Iodine-125 seed implantation in lymph node as a novel therapy for MCAO: A case report.
作者信息
Qian Huiwen, Jin Jianqiang, Wang Changguo, Wang Yuting, Ge Juxiang, Huang Jianan, Ji Cheng
机构信息
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, China.
出版信息
Medicine (Baltimore). 2025 Jan 17;104(3):e41198. doi: 10.1097/MD.0000000000041198.
RATIONALE
We report here a case of using iodine-125 (125I) seed implantation via endobronchial ultrasound (EBUS) in the treatment of malignant central airway obstruction (MCAO) in a patient with lung adenocarcinoma.
PATIENT CONCERNS
The patient still experienced MCAO after conventional bronchoscopic interventional therapy.
DIAGNOSES
The patient was diagnosed as lung adenocarcinoma stage IV (T4N2M1a).
INTERVENTIONS
She received implantation of radioactive 125I seeds in the lesion inside the right middle lobe bronchus and 12R lymph node via bronchoscopy and EBUS, in combination with chemotherapy and immunotherapy.
OUTCOMES
The patient's MCAO has been effectively controlled.
LESSONS
The success of this case suggests that EBUS-guided 125I seed implantation to lymph nodes is a safe and effective therapeutic option for MCAO.
原理
我们在此报告一例通过支气管内超声（EBUS）进行碘-125（¹²⁵I）粒子植入治疗肺腺癌患者恶性中央气道阻塞（MCAO）的病例。
患者情况
患者在接受传统支气管镜介入治疗后仍存在MCAO。
诊断
患者被诊断为IV期肺腺癌（T4N2M1a）。
干预措施
她通过支气管镜和EBUS在右中叶支气管内病变及12R淋巴结植入放射性¹²⁵I粒子，并联合化疗和免疫治疗。
结果
患者的MCAO得到有效控制。
经验教训
该病例的成功表明，EBUS引导下向淋巴结植入¹²⁵I粒子是治疗MCAO的一种安全有效的治疗选择。
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