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Melatonin: a positive influencer of inflammation in neonatal encephalopathy.

作者信息

Pang Raymand, Molloy Eleanor, Robertson Nicola J

机构信息

Institute for Women's Health, University College London, WC1E 6HX, 74 Huntley Street, London, WC1E 6HX, UK.

Discipline of Paediatrics, Trinity College Dublin, The University of Dublin, Trinity Translational Medicine Institute (TTMI), St James Hospital & Trinity Research in Childhood Centre (TRiCC), Dublin, Ireland.

出版信息

Pediatr Res. 2025 Jan 20. doi: 10.1038/s41390-025-03876-7.

DOI:10.1038/s41390-025-03876-7
PMID:39833346
Abstract
摘要

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本文引用的文献

1
Pro-inflammatory biomarkers and long term neurological outcomes in hypothermia plus melatonin treated asphyxiated newborns. A preliminary approach.低温联合褪黑素治疗窒息新生儿的促炎生物标志物与长期神经学转归：初步研究
Pediatr Res. 2024 Nov 23. doi: 10.1038/s41390-024-03742-y.
2
Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review.围产期窒息的关键炎症生物标志物：全面综述。
Clin Perinatol. 2024 Sep;51(3):617-628. doi: 10.1016/j.clp.2024.04.004. Epub 2024 May 22.
3
Melatonin reduces brain injury following inflammation-amplified hypoxia-ischemia in a translational newborn piglet study of neonatal encephalopathy.
在一项关于新生儿脑病的新生仔猪转化研究中，褪黑素可减轻炎症放大的缺氧缺血后的脑损伤。
J Pineal Res. 2024 May;76(4):e12962. doi: 10.1111/jpi.12962.
4
Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III).ALBINO 研究的详细统计分析计划：别嘌呤醇联合亚低温治疗缺氧缺血性脑损伤对神经认知结局的影响 - 一项针对优效性的盲法随机安慰剂对照平行分组多中心临床试验（III 期）。
Trials. 2024 Jan 24;25(1):81. doi: 10.1186/s13063-023-07828-6.
5
Melatonin Alters Innate Immune Function in Infants with Neonatal Encephalopathy.褪黑素改变新生儿脑病婴儿的固有免疫功能。
Neonatology. 2023;120(3):325-333. doi: 10.1159/000527714. Epub 2023 Jun 15.
6
Neuroprotective therapies in the NICU in term infants: present and future.新生儿重症监护病房中足月婴儿的神经保护治疗：现状与未来。
Pediatr Res. 2023 Jun;93(7):1819-1827. doi: 10.1038/s41390-022-02295-2. Epub 2022 Oct 4.
7
Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns.新生儿缺氧缺血性脑病促红细胞生成素治疗试验。
N Engl J Med. 2022 Jul 14;387(2):148-159. doi: 10.1056/NEJMoa2119660.
8
Efficacy of melatonin in term neonatal models of perinatal hypoxia-ischaemia.褪黑素对围产期缺氧缺血足月新生儿模型的疗效。
Ann Clin Transl Neurol. 2022 Jun;9(6):795-809. doi: 10.1002/acn3.51559. Epub 2022 Apr 12.
9
Redox Biology of Melatonin: Discriminating Between Circadian and Noncircadian Functions.褪黑素的氧化还原生物学：区分昼夜节律和非昼夜节律功能。
Antioxid Redox Signal. 2022 Oct;37(10-12):704-725. doi: 10.1089/ars.2021.0275. Epub 2022 Feb 10.
10
Melatonin as an immunomodulator in children with Down syndrome.褪黑素作为唐氏综合征儿童的免疫调节剂。
Pediatr Res. 2022 Jun;91(7):1812-1820. doi: 10.1038/s41390-021-01611-6. Epub 2021 Aug 16.