Carneiro Mailon Cury, de Abreu Lukas Mendes, Paludetto Laura Vidoto, da Silva Santos Paulo Sérgio, Rubira-Bullen Izabel Regina Fischer, Rubira Cássia Maria Fischer
Department of Surgery, Stomatology, Pathology, and Radiology, Bauru School of Dentistry, University of São Paulo. Alameda Octávio Pinheiro Brisolla, Bauru 9-75, Bauru, SP, 17012-901, Brazil.
Oral Radiol. 2025 Jan 20. doi: 10.1007/s11282-025-00803-8.
This retrospective study compared the thickness and degree of resorption of the mandibular cortex in patients with head and neck cancer (AG), patients with cancer at sites other than the head and neck (BG), and patients with no cancer (CG) to describe and compare the changes in the mandible after antineoplastic therapy and their possible clinical implications.
A total of 287 panoramic radiographs were examined. The following radiomorphometric indices were analyzed: mental index (MI), panoramic mandibular index (PMI), and mandibular cortical index (MCI). Analysis of variance (ANOVA) and the Kruskal‒Wallis test, with p < 0.05 considered significant, were performed.
Males predominated in the AG (83%), while females predominated in the BG and CG (78.6 and 62%, respectively). In the AG, tongue carcinoma (22.1%) was prevalent, while in the BG, breast carcinoma was predominant (53.8%). All parameters measured in the AG and BG patients were significantly lower than those in the CG patients: MI (p < 0.001), right PMIc/a (p < 0.001), left PMIc/a (p < 0.001), right PMIc/b (p = 0.004), left PMIc/b (p < 0.001), and MCI (p < 0.001).
Radiomorphometric indices MI, PMI, and MCI were significantly lower in panoramic radiographs of patients with head and neck cancer and patients with cancer in other regions of the body than in those of nononcological patients.
本回顾性研究比较了头颈癌患者（AG组）、非头颈部位癌症患者（BG组）和无癌症患者（CG组）下颌骨皮质的厚度和吸收程度，以描述和比较抗肿瘤治疗后下颌骨的变化及其可能的临床意义。
共检查了287张全景X线片。分析了以下放射形态计量学指标：颏孔指数（MI）、全景下颌指数（PMI）和下颌骨皮质指数（MCI）。进行方差分析（ANOVA）和Kruskal-Wallis检验，p < 0.05认为具有统计学意义。
AG组男性占主导（83%），而BG组和CG组女性占主导（分别为78.6%和62%）。AG组中舌癌（22.1%）最为常见，而BG组中乳腺癌占主导（53.8%）。AG组和BG组患者测量的所有参数均显著低于CG组患者：MI（p < 0.001）、右侧PMIc/a（p < 0.001）、左侧PMIc/a（p < 0.001）、右侧PMIc/b（p = 0.004）、左侧PMIc/b（p < 0.001）和MCI（p < 0.001）。
头颈癌患者和身体其他部位癌症患者全景X线片中的放射形态计量学指标MI、PMI和MCI显著低于非肿瘤患者。
