Smith Caraleigh G, Clowers Brian H, Kregel Steven J
Mund-Lagowski Department of Chemistry and Biochemistry, Bradley University, Peoria, Illinois 61625, United States.
Washington State University, Department of Chemistry, Pullman, Washington 99164, United States.
J Am Soc Mass Spectrom. 2025 Feb 5;36(2):236-240. doi: 10.1021/jasms.4c00410. Epub 2025 Jan 20.
In this communication we report the construction of a printed circuit board which mounts directly to the vacuum chamber of a mass spectrometer and produces the RF waveforms needed by many nonmass-selective devices such as ion guides and ion funnels. Our device is designed to replace a standard KF40 flange, can maintain vacuum chamber pressures of less than 10 Torr, and contains the circuitry of the open-source Wisconsin Oscillator RF power supply to generate RF waveforms of 1-4 MHz and up to 200 V. In this iteration of the Wisconsin Oscillator, we also introduce a variable resistor to control the output RF amplitude and show that its ion transmission capabilities are identical to those provided by commercial RF power supplies. With this new implementation we have greatly reduced the space and monetary requirements for driving nonmass-selective ion manipulation devices, which we expect to be advantageous to those developing low-cost and/or portable mass spectrometry systems.
在本通讯中，我们报告了一种印刷电路板的构建，该电路板可直接安装到质谱仪的真空腔上，并产生许多非质量选择设备（如离子导向器和离子漏斗）所需的射频波形。我们的设备旨在取代标准的KF40法兰，能够保持真空腔压力低于10托，并包含开源威斯康星振荡器射频电源的电路，以生成1 - 4 MHz、高达200 V的射频波形。在威斯康星振荡器的这一迭代中，我们还引入了一个可变电阻来控制输出射频幅度，并表明其离子传输能力与商用射频电源提供的能力相同。通过这种新的实现方式，我们大大降低了驱动非质量选择离子操纵设备的空间和资金需求，我们预计这对开发低成本和/或便携式质谱系统的人员将是有利的。
