• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肺部之外:经化疗、手术清创和融合治疗的跗跖关节结核罕见病例报告

Beyond the Lung: A Rare Presentation of Tuberculosis in the Tarsometatarsal Joint Treated With Chemotherapy, Surgical Debridement, and Fusion.

作者信息

Sam Arun, Kumar Saravana, Shankar Raja

机构信息

Orthopaedics and Traumatology, District Headquarters Hospital, Cuddalore, IND.

出版信息

Cureus. 2024 Dec 19;16(12):e76011. doi: 10.7759/cureus.76011. eCollection 2024 Dec.

DOI:10.7759/cureus.76011
PMID:39835012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11743471/
Abstract

Foot tuberculosis is rarely reported in the literature, with most tuberculosis of the foot being an uncommon manifestation of skeletal tuberculosis. Early diagnosis and timely medical and surgical intervention can significantly reduce morbidity. A 23-year-old male presented with persistent swelling and pain in his right foot for six months, accompanied by a discharging sinus over the affected area in the last week, making weight-bearing increasingly difficult. Examination revealed cystic swelling near the cuboid bone, along with constitutional symptoms. Imaging studies, including X-ray and CT, showed osteopenia, bony erosions, and subluxation of the calcaneocuboid joint. MRI identified an abscess on the lateral aspect of the foot. Although aspiration and swab cultures were negative, the patient was empirically started on antitubercular therapy (ATT). Surgical debridement and fusion of the calcaneocuboid joint were performed using K-wires and tricortical bone grafts. A biopsy confirmed the diagnosis of tuberculosis. After completing nine months of ATT, the patient showed significant improvement, achieving a healthy scar and a functional plantigrade foot. Biopsy and synovectomy, combined with chemotherapy, are essential treatments for skeletal tuberculosis. The interconnected nature of midfoot joints allows untreated osseous disease to spread, potentially causing joint instability, restricted movement, and poor functional outcomes. Early joint stabilization in the correct alignment is vital to prevent deformities. Similar to spinal tuberculosis management, radical debridement and bone grafting are effective in midfoot tuberculosis. Debridement reduces the infectious load, while bone grafting provides a stable framework to minimize recurrence and promote joint fusion. This approach not only alleviates pain but also enhances the patient's functional recovery.

摘要

足部结核在文献中鲜有报道,足部的大多数结核是骨结核的罕见表现。早期诊断以及及时的药物和手术干预可显著降低发病率。一名23岁男性,右脚持续肿胀疼痛6个月,上周患区出现排脓窦道,负重越来越困难。检查发现骰骨附近有囊性肿胀,并伴有全身症状。包括X线和CT在内的影像学检查显示骨质减少、骨质侵蚀以及跟骰关节半脱位。磁共振成像(MRI)发现足部外侧有脓肿。尽管穿刺抽吸和拭子培养结果为阴性,但仍经验性地给予该患者抗结核治疗(ATT)。使用克氏针和三面皮质骨移植对跟骰关节进行了手术清创和融合。活检确诊为结核。完成9个月的抗结核治疗后,患者有显著改善,形成健康瘢痕,足部功能良好。活检和滑膜切除术,联合化疗,是骨结核的重要治疗方法。中足关节相互关联的特性使得未经治疗的骨病得以扩散,可能导致关节不稳定、活动受限和功能预后不良。早期以正确的对线方式进行关节稳定对于预防畸形至关重要。与脊柱结核的治疗相似,根治性清创和植骨对中足结核有效。清创可减少感染负荷,而植骨提供稳定的框架以尽量减少复发并促进关节融合。这种方法不仅能缓解疼痛,还能促进患者的功能恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/e435e24b4428/cureus-0016-00000076011-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/226f821c7455/cureus-0016-00000076011-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/69aad22b52fb/cureus-0016-00000076011-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/877c7e41a51d/cureus-0016-00000076011-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/4b9f9d361944/cureus-0016-00000076011-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/4b3fc0e3caba/cureus-0016-00000076011-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/a571ed0ab99d/cureus-0016-00000076011-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/b4814c0da828/cureus-0016-00000076011-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/c25fb9633fef/cureus-0016-00000076011-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/e435e24b4428/cureus-0016-00000076011-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/226f821c7455/cureus-0016-00000076011-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/69aad22b52fb/cureus-0016-00000076011-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/877c7e41a51d/cureus-0016-00000076011-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/4b9f9d361944/cureus-0016-00000076011-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/4b3fc0e3caba/cureus-0016-00000076011-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/a571ed0ab99d/cureus-0016-00000076011-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/b4814c0da828/cureus-0016-00000076011-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/c25fb9633fef/cureus-0016-00000076011-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/08d7/11743471/e435e24b4428/cureus-0016-00000076011-i09.jpg

相似文献

1
Beyond the Lung: A Rare Presentation of Tuberculosis in the Tarsometatarsal Joint Treated With Chemotherapy, Surgical Debridement, and Fusion.肺部之外:经化疗、手术清创和融合治疗的跗跖关节结核罕见病例报告
Cureus. 2024 Dec 19;16(12):e76011. doi: 10.7759/cureus.76011. eCollection 2024 Dec.
2
Isolated calcaneocuboid joint tuberculosis: a rare case report.孤立性跟骰关节结核:1例罕见病例报告
Foot (Edinb). 2013 Dec;23(4):169-71. doi: 10.1016/j.foot.2013.10.001. Epub 2013 Oct 11.
3
Sacroiliac joint tuberculosis: surgical management by posterior open-window focal debridement and joint fusion.骶髂关节结核:经后路开窗病灶清除及关节融合术的外科治疗
BMC Musculoskelet Disord. 2017 Nov 29;18(1):504. doi: 10.1186/s12891-017-1866-9.
4
Osteoarticular tuberculous infection of the first tarsometatarsal joint - a case report.第一跖跗关节骨关节结核感染——病例报告
Int J Surg Case Rep. 2022 Sep;98:107582. doi: 10.1016/j.ijscr.2022.107582. Epub 2022 Sep 3.
5
Operative treatment of the difficult stage 2 adult acquired flatfoot deformity.成人获得性平足畸形二期困难阶段的手术治疗
Foot Ankle Clin. 2001 Mar;6(1):95-119. doi: 10.1016/s1083-7515(03)00083-4.
6
Tubercular osteomyelitis of calcaneum in an immunocompetent adult.成人免疫功能正常者的跟骨结核性骨髓炎。
Int J Mycobacteriol. 2023 Oct-Dec;12(4):501-504. doi: 10.4103/ijmy.ijmy_162_23.
7
Craniocervical tuberculosis: protocol of surgical management.颅颈结核:外科治疗方案
Neurosurgery. 2003 Jan;52(1):72-80; discussion 80-1.
8
Complete debridement for treatment of thoracolumbar spinal tuberculosis: a clinical curative effect observation.彻底清创术治疗胸腰椎脊柱结核:临床疗效观察
Spine J. 2014 Jun 1;14(6):964-70. doi: 10.1016/j.spinee.2013.07.466. Epub 2013 Oct 8.
9
Efficacy analysis of anterior debridement and bone graft fusion in the treatment of sacroiliac joint tuberculous arthritis: a retrospective analysis of 17 patients.前路清创植骨融合术治疗骶髂关节结核性关节炎的疗效分析:17 例回顾性分析。
BMC Musculoskelet Disord. 2022 Jul 5;23(1):645. doi: 10.1186/s12891-022-05600-6.
10
Role of Surgery in Management of Osteo-Articular Tuberculosis of the Foot and Ankle.手术在足踝部骨关节结核治疗中的作用
Open Orthop J. 2017 Jul 31;11:633-650. doi: 10.2174/1874325001711010633. eCollection 2017.

本文引用的文献

1
Diagnosis and treatment of tuberculosis of the foot and ankle-A literature review.足踝部结核的诊断与治疗——文献综述
Foot (Edinb). 2018 Dec;37:105-112. doi: 10.1016/j.foot.2018.07.005. Epub 2018 Jul 25.
2
Role of Surgery in Management of Osteo-Articular Tuberculosis of the Foot and Ankle.手术在足踝部骨关节结核治疗中的作用
Open Orthop J. 2017 Jul 31;11:633-650. doi: 10.2174/1874325001711010633. eCollection 2017.
3
Anterior debridement and bone grafting of spinal tuberculosis with one-stage instrumentation anteriorly or posteriorly.
脊柱结核前路清创及植骨并一期前路或后路内固定。
Int Orthop. 2007 Dec;31(6):859-63. doi: 10.1007/s00264-006-0253-1. Epub 2006 Oct 24.