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伴有快速进展性帕金森病的血清阴性自身免疫性脑炎

Seronegative Autoimmune Encephalitis With Rapidly Progressive Parkinsonism.

作者信息

Mallick Richa, Rao Abhijith, Digra Vasu, Kumar Pramod, Chakrawarty Avinash

机构信息

Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.

出版信息

Cureus. 2024 Dec 21;16(12):e76114. doi: 10.7759/cureus.76114. eCollection 2024 Dec.

Abstract

Seronegative autoimmune encephalitis is an infrequent entity in older patients, and its presentation as rapidly progressive parkinsonism is rarely seen in cases of autoimmune encephalitis. We present a case report of an older patient who presented with worsening Parkinson's-like symptoms over a month. We highlight the importance of considering autoimmune encephalitis as a potential cause of rapidly progressive parkinsonism and the importance of radiological findings when the entire autoimmune panel is negative in such patients.

摘要

血清阴性自身免疫性脑炎在老年患者中并不常见,而其表现为快速进展性帕金森症在自身免疫性脑炎病例中则很少见。我们报告一例老年患者,其在一个月内出现类似帕金森症的症状且逐渐加重。我们强调,对于快速进展性帕金森症患者,当整个自身免疫检查结果均为阴性时,考虑自身免疫性脑炎作为潜在病因的重要性以及影像学检查结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f67f/11744400/3c2de462aca3/cureus-0016-00000076114-i01.jpg

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