Aleid Abdulsalam M, Aldanyowi Saud N, AlAidarous Hasan A, Aleid Zainab M, Alharthi Abdulaziz S, Al Mutair Abbas
Department of Surgery, Medical College, King Faisal University, Hofuf, Ahsa, KSA.
Department of Surgery, Faculty of Medicine, Albaha University, KSA.
J Taibah Univ Med Sci. 2024 Dec 12;20(1):13-24. doi: 10.1016/j.jtumed.2024.12.003. eCollection 2025 Feb.
Perthes disease presents a challenge in orthopedic management, often necessitating surgical intervention such as arthroplasty. This meta-analysis systematically evaluated the rate of occurrence and complications associated with arthroplasty in Perthes disease.
A comprehensive search was conducted across PubMed, Web of Sciences, Scopus, and Cochrane Library databases to identify relevant studies. Inclusion criteria encompassed studies evaluating arthroplasty outcomes in patients with Perthes disease. Data extraction and quality assessment were performed independently by two reviewers. Results were synthesized using random effects models, and heterogeneity was assessed using I statistics. Twenty-eight observational studies were included with a total of 1737 patients, reporting moderate heterogeneity.
We found that the incidence of arthroplasty among the 18 studies included in the meta-analysis was 7 % (95 % confidence interval [CI]: 0.045-0.95, I = 58 %). Complications following arthroplasty were significant with an incidence of 22.9 % among 283 patients. In summary, an analysis of 30 observational studies found a 7 % incidence of arthroplasty with complications following surgery affecting nearly 23 % of patients.
The results of this study suggest that arthroplasty is a relatively uncommon procedure for Perthes disease management. Complications following arthroplasty are a significant concern, affecting nearly one-quarter of patients. Although the use of arthroplasty in Perthes is uncommon, the rate of complications has raised concerns, indicating its use is relatively unsafe. Therefore, in patients with Perthes disease who undergo arthroplasty, attention should be given to the risk of complications, and preventive measures need to be investigated to overcome this risk.
Systematic review and meta-analysis.
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佩特兹病在骨科治疗中具有挑战性，通常需要进行诸如关节成形术等手术干预。本荟萃分析系统评价了佩特兹病关节成形术的发生率及相关并发症。
全面检索了PubMed、科学网、Scopus和考克兰图书馆数据库以识别相关研究。纳入标准包括评估佩特兹病患者关节成形术结局的研究。由两名 reviewers 独立进行数据提取和质量评估。采用随机效应模型综合结果，并使用I统计量评估异质性。纳入了28项观察性研究，共1737例患者，报告存在中度异质性。
我们发现，纳入荟萃分析的18项研究中关节成形术的发生率为7%（95%置信区间[CI]：0.045 - 0.95，I = 58%）。关节成形术后并发症显著，283例患者中的发生率为22.9%。总之，对30项观察性研究的分析发现关节成形术的发生率为7%，术后并发症影响了近23%的患者。
本研究结果表明，关节成形术是佩特兹病治疗中相对不常见的手术。关节成形术后并发症是一个重大问题，影响了近四分之一的患者。尽管在佩特兹病中使用关节成形术并不常见，但并发症发生率令人担忧，表明其使用相对不安全。因此，对于接受关节成形术的佩特兹病患者，应关注并发症风险，并需研究预防措施以克服此风险。
系统评价和荟萃分析。
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