The Sound of Silence: Suppressing CBX5 Decreases Fibrosis by Inhibiting Fibroblasts.
作者信息
Rojas Mauricio, Mora Ana L
机构信息
Division of Pulmonary, Critical Care and Sleep The Ohio State University Columbus, Ohio.
出版信息
Am J Respir Cell Mol Biol. 2025 Jun;72(6):605-606. doi: 10.1165/rcmb.2024-0618ED.
Abstract
摘要
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本文引用的文献
1
Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis.
Am J Respir Cell Mol Biol. 2025 Jun;72(6):627-642. doi: 10.1165/rcmb.2024-0255OC.
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Alveolar fibroblast lineage orchestrates lung inflammation and fibrosis.
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CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.
JCI Insight. 2019 May 16;5(12):127111. doi: 10.1172/jci.insight.127111.
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