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间歇性记录血压值并不能全面评估持续静脉给药期间的血流动力学反应。

Intermittent documentation of blood pressure values does not provide comprehensive evaluation of the hemodynamic response during continuous intravenous medication administration.

作者信息

Doyle Brittany R, Nairon Emerson B, Jones Erica, Salter Amber, Olson DaiWai M

机构信息

Department of Nursing, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

出版信息

Sci Rep. 2025 Jan 21;15(1):2741. doi: 10.1038/s41598-025-87606-3.

DOI:10.1038/s41598-025-87606-3
PMID:39838053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751090/
Abstract

Blood pressure (BP) is a dynamic measure that is frequently discussed in static terms. There exist many limitations in current documentation systems whereby documented BP values may not be reflective of the dynamic variability of BP. This study used an observational, prospective, non-randomized study design to examine the variability in BP response during intravenous vasoactive medication administration in an intensive care unit setting. Subjects admitted to a neuroscience intensive care unit were monitored continuously during a 12-hour period. The BP values include systolic BP, diastolic BP, and mean arterial pressure. Intermittent values from an intra-arterial figurecatheter (a-line) and continuously sampled values from an a-line obtained using continuous data acquisition (CDA) software, were compared to intermittently sampling of cuff-based BP measurements documented in the medical record. The 30 patients provided 1,220,511 BP observations from CDA, 944 from a-line documentation, and 416 from cuff-based BP documentation. The systolic BP was used as a goal parameter for 23 (77%) of the patients. Repeated measures models demonstrated that on average cuff-based differed from intermittent a-line and from CDA (p < .005) for all BP values. No differences between a-line and CDA were observed. Concordance correlation coefficients ranged from 0.56 to 0.72 for a-line, cuff-based BP, and CDA, indicating moderate agreement. Using intermittently documented BP values does not fully represent the dynamic nature of BP over time.

摘要

血压(BP)是一种动态测量指标,但人们常常以静态方式进行讨论。当前的记录系统存在许多局限性,记录的血压值可能无法反映血压的动态变化。本研究采用观察性、前瞻性、非随机研究设计,以检查重症监护病房环境中静脉使用血管活性药物期间血压反应的变异性。入住神经科学重症监护病房的受试者在12小时内持续接受监测。血压值包括收缩压、舒张压和平均动脉压。将来自动脉内压力导管(a线)的间歇性值以及使用连续数据采集(CDA)软件从a线获得的连续采样值,与病历中记录的基于袖带的血压测量的间歇性采样值进行比较。30名患者提供了来自CDA的1,220,511次血压观察数据﹑来自a线记录的944次数据以及来自基于袖带的血压记录的416次数据。23名(77%)患者将收缩压用作目标参数。重复测量模型表明,对于所有血压值,基于袖带的测量值与间歇性a线测量值和CDA测量值平均存在差异(p < 0.005)。未观察到a线和CDA之间存在差异。a线、基于袖带的血压和CDA的一致性相关系数在0.56至0.72之间,表明一致性中等。使用间歇性记录的血压值不能完全代表血压随时间的动态特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f3/11751090/c4afec7eef27/41598_2025_87606_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f3/11751090/a17c4b7cdd3e/41598_2025_87606_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f3/11751090/c4afec7eef27/41598_2025_87606_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f3/11751090/a17c4b7cdd3e/41598_2025_87606_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f3/11751090/c4afec7eef27/41598_2025_87606_Fig2_HTML.jpg

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