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美国有医学推荐使用大麻和非医学使用大麻人群中大麻消费方式的流行情况。

Prevalence of cannabis consumption methods among people with medically recommended and nonmedical cannabis use in the United States.

作者信息

Han Beth, Jones Christopher M, Volkow Nora D, Einstein Emily B, Weiss Susan R B, Blanco Carlos, Compton Wilson M

机构信息

National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, United States.

Substance Abuse and Mental Health Services Administration, Rockville, MD, United States.

出版信息

Addiction. 2025 May;120(5):962-974. doi: 10.1111/add.16741. Epub 2025 Jan 21.

Abstract

AIMS

Some cannabis consumption methods (e.g. smoking, vaping, dabbing) are associated with more harms than others (e.g. sublingual, transdermal). We aimed to examine differences in prevalence of cannabis consumption methods by people with medically recommended-only vs. nonmedical-only cannabis use.

DESIGN AND SETTING

Cross-sectional, US nationally representative data from the 2022 National Survey on Drug Use and Health (NSDUH).

PARTICIPANTS

14 271 NSDUH participants aged ≥12 with past-year cannabis use.

MEASUREMENTS

NSDUH asked respondents with past-year cannabis use about their consumption methods [i.e. smoking, vaping, eating or drinking, dabbing (consuming a concentrated form with a dab rig/pen), oral/sublingual, transdermal or taking pills] and if healthcare professionals recommended any cannabis use. If 'no', respondents were classified as having 'nonmedical-only cannabis use'. If 'yes', they were asked if all cannabis use was recommended and, if so, they were classified as having 'medically recommended-only cannabis use'; otherwise, they were classified as having 'medical and nonmedical cannabis use'.

FINDINGS

Among people reporting cannabis use, 10.7% [95% confidence interval (CI) = 9.7%-11.7%] reported medically recommended-only use, and 83.0% (95% CI = 81.7%-84.3%) reported nonmedical-only use. Smoking was the predominant method for nonmedical-only use (79.2%, 95% CI = 77.7%-80.7%) and for medically recommended-only use (73.7%, 95% CI = 68.8%-78.2%). Vaping prevalence (45.6%, 95% CI = 40.9%-50.4%) and eating/drinking prevalence (45.7%, 95% CI = 40.7%-50.7%) were similar among people with medically recommended-only use. Vaping prevalence was 1.3 times higher [adjusted prevalence ratio (APR) = 1.3, 95% CI = 1.2-1.4] for medically recommended-only than for nonmedical-only use (38.3%, 95% CI = 32.7%-44.3%). Dabbing prevalence was 1.5 times higher (APR = 1.5, 95% CI = 1.3-1.7) for medically recommended-only than for nonmedical-only use [24.4% (95% CI = 20.5%-28.8%) vs 16.4% (95% CI = 15.3%-17.7%)]. Higher prevalence of oral/sublingual and transdermal methods was associated with medically recommended-only use.

CONCLUSIONS

Among people with past-year medically recommended-only cannabis use in the US, three-fourths reported smoking cannabis and almost half reported vaping and eating/drinking cannabis. Cannabis vaping prevalence and dabbing prevalence were 1.3-1.5 times higher, respectively, among people with medically recommended-only use than people with nonmedical-only use.

摘要

目的

某些大麻消费方式(如吸烟、雾化、滴吸)比其他方式(如舌下含服、透皮给药)危害更大。我们旨在研究仅出于医学推荐使用大麻的人群与仅非医学使用大麻的人群在大麻消费方式流行率上的差异。

设计与背景

横断面研究,数据来自2022年美国全国药物使用和健康调查(NSDUH),具有全国代表性。

参与者

14271名年龄≥12岁、过去一年使用过大麻的NSDUH参与者。

测量方法

NSDUH询问过去一年使用过大麻的受访者其消费方式[即吸烟、雾化、食用或饮用、滴吸(使用滴吸装置/笔吸食浓缩形式)、口服/舌下含服、透皮给药或服用药丸],以及医疗保健专业人员是否推荐过任何大麻使用。如果回答“否”,受访者被归类为“仅非医学使用大麻”。如果回答“是”,则询问其所有大麻使用是否都有推荐,如果是,则被归类为“仅出于医学推荐使用大麻”;否则,被归类为“医学和非医学使用大麻”。

研究结果

在报告使用过大麻的人群中,10.7%[95%置信区间(CI)=9.7%-11.7%]报告仅出于医学推荐使用,83.0%(95%CI=81.7%-84.3%)报告仅非医学使用。吸烟是仅非医学使用(79.2%,95%CI=77.7%-80.7%)和仅出于医学推荐使用(73.7%,95%CI=68.8%-78.2%)的主要方式。在仅出于医学推荐使用大麻的人群中,雾化流行率(45.6%,95%CI=40.9%-50.4%)和食用/饮用流行率(45.7%,95%CI=40.7%-50.7%)相似。仅出于医学推荐使用大麻的人群的雾化流行率比仅非医学使用大麻的人群高1.3倍[调整后流行率比(APR)=1.3,95%CI=1.2-1.4](38.3%,95%CI=32.7%-44.3%)。仅出于医学推荐使用大麻的人群的滴吸流行率比仅非医学使用大麻的人群高1.5倍(APR=1.5,95%CI=1.3-1.7)[24.4%(95%CI=20.5%-28.8%)对16.4%(95%CI=15.3%-17.7%)]。口服/舌下含服和透皮给药方式的较高流行率与仅出于医学推荐使用有关。

结论

在美国过去一年仅出于医学推荐使用大麻的人群中,四分之三报告吸食大麻,近一半报告雾化和食用/饮用大麻。仅出于医学推荐使用大麻人群的大麻雾化流行率和滴吸流行率分别比仅非医学使用大麻人群高1.3至1.5倍。

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