Albuquerque Andreia, Rao Satish S C
School of Medicine and Biomedical Sciences, Fernando Pessoa University, Gondomar 4420-096, Porto, Portugal.
Precancerous Lesions and Early Cancer Management Research Group RISE@CI-IPO (Health Research Network), Portuguese Oncology Institute of Porto, Porto 4200-072, Portugal.
World J Gastroenterol. 2025 Jan 21;31(3):97963. doi: 10.3748/wjg.v31.i3.97963.
Fecal incontinence is a common condition that can significantly impact patients' quality of life. Obstetric anal sphincter injury and anorectal surgeries are common etiologies. Endoanal ultrasound and anorectal manometry are important diagnostic tools for evaluating patients. There are various treatment options, including diet, lifestyle modifications, drugs, biofeedback therapy, tibial and sacral nerve neuromodulation therapy, and surgery. In this editorial, we will discuss current controversies and novel approaches to fecal incontinence. Screening for asymptomatic anal sphincter defects after obstetric anal sphincter injury and in patients with inflammatory bowel disease is not generally recommended, but may be helpful in selected patients. The Garg incontinence score is a new score that includes the assessment of solid, liquid, flatus, mucous, stress and urge fecal incontinence. Novel tests such as translumbosacral anorectal magnetic stimulation and novel therapies such as translumbosacral neuromodulation therapy are promising diagnostic and treatment options, for both fecal incontinence and neuropathy. Home biofeedback therapy can overcome some limitations of the office-based therapy. Skeletal muscle-derived cell implantation of the external anal sphincter has been further studied as a possible treatment option. Sacral neuromodulation may be useful in scleroderma, congenital fecal incontinence and inflammatory bowel disease but merits further study.
大便失禁是一种常见病症,会对患者的生活质量产生重大影响。产科肛门括约肌损伤和肛肠手术是常见病因。肛管超声检查和肛肠测压是评估患者的重要诊断工具。有多种治疗选择,包括饮食、生活方式调整、药物、生物反馈疗法、胫神经和骶神经神经调节疗法以及手术。在这篇社论中,我们将讨论大便失禁的当前争议和新方法。一般不建议在产科肛门括约肌损伤后及炎症性肠病患者中筛查无症状肛门括约肌缺陷,但对特定患者可能有帮助。加尔格失禁评分是一种新评分,包括对固体、液体、气体、黏液、压力性和急迫性大便失禁的评估。诸如经腰骶部肛肠磁刺激等新测试以及诸如经腰骶部神经调节疗法等新疗法,对于大便失禁和神经病变而言,都是有前景的诊断和治疗选择。家庭生物反馈疗法可以克服门诊治疗的一些局限性。作为一种可能的治疗选择,对肛门外括约肌进行骨骼肌来源细胞植入已得到进一步研究。骶神经调节在硬皮病、先天性大便失禁和炎症性肠病中可能有用,但值得进一步研究。