脉冲电场（PEF）治疗难治性外阴黑色素瘤并同时接受免疫检查点阻断治疗显示出远隔效应：一例病例报告。
Pulsed electric field (PEF) treatment of refractory vulvar melanoma concurrently treated with immune checkpoint blockade demonstrating an abscopal response: A case report.
作者信息
Knight Daniel B, Hillard Hannah, Handran Chauncy, Kuhlman Patrick
机构信息
Prisma Health Cancer Institute, Greenville, SC 29605, USA.
Prisma Health Internal Medicine Department, University of South Carolina, Greenville, SC 29605, USA.
出版信息
Gynecol Oncol Rep. 2024 Dec 27;57:101671. doi: 10.1016/j.gore.2024.101671. eCollection 2025 Feb.
Abstract
•Vulvar melanoma is deadlier and harder to treat than typical melanoma.•82-year-old female had metastatic vulvar melanoma that reoccurred on immunotherapy.•Treatment with pulsed electric field therapy led to rapid resolution of metastatic disease.•Pulsed electric field therapy can drive early remission in solid tumors.
摘要
•外阴黑色素瘤比典型黑色素瘤更致命且更难治疗。
•一名82岁女性患有转移性外阴黑色素瘤，在免疫治疗后复发。
•脉冲电场疗法治疗导致转移性疾病迅速缓解。
•脉冲电场疗法可促使实体瘤早期缓解。
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